Lawrenson J B, Kalis N N, Pribut H, Hewitson J, Shipton S, Stirling J, De Decker R
Division of Critical Care and Children's Heart Disease, School of Adolescent and Child Health, University of Cape Town, Tygerberg, Western Cape, South Africa.
S Afr Med J. 2006 Sep;96(9 Pt 2):914-9.
About 1 in 1,000 children has Down syndrome. Extra chromosomal material results in a myriad of potential problems for the affected individual. About 40% of Down syndrome children will have cardiac abnormalities, ranging from the simple arterial duct to the complex atrioventricular septal defect. Virtually all these defects are amenable to surgical correction and extended survival is possible. In South Africa many of these children do not undergo cardiac surgery.
每1000名儿童中约有1名患有唐氏综合征。额外的染色体物质会给受影响的个体带来无数潜在问题。约40%的唐氏综合征儿童会有心脏异常，从简单的动脉导管未闭到复杂的房室间隔缺损不等。几乎所有这些缺陷都可以通过手术矫正，延长生存期是可能的。在南非，许多这样的儿童没有接受心脏手术。
