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多发性发育不全与无汗性外胚层发育不良:两组儿童牙齿相似性与基因差异的比较纵向研究

Multiple agenesis and anhidrotic ectodermal dysplasia: a comparative longitudinal study of dental similarities and genetic differences in two groups of children.

作者信息

Barbería E, Saavedra D, Arenas M, Maroto M

机构信息

Department of Prophylaxis, Paediatric Dentistry and Orthodontics, Faculty of Odontology, Madrid Complutense University, Madrid, Spain.

出版信息

Eur J Paediatr Dent. 2006 Sep;7(3):113-21.

Abstract

AIM

Dental anomalies in shape and number may be present isolated or associated with other manifestations. In anhidrotic ectodermal dysplasia they occur more frequently and severely. The authors examined a group of children with similar dental anomalies but no other ectodermal or extra-ectodermal signs.

METHODS

This study makes a comparative evaluation of similarities and differences of dental anomalies between two groups: A anhidrotic ectodermal dysplasia and B similar dental finding but without extra- dental anomalies.

RESULTS

In group A, the average number of agenesis in primary teeth was 3.5 (upper) and 5.33 (lower); in permanent teeth it was 5.4 and 5.8, respectively. In group B, the average was 1.62 (upper) and 0.25 (lower) in primary teeth, and 4.0 and 4.25 in permanent teeth respectively, with no constant pattern of occurrence. The study of tooth morphology of both groups revealed numerous anomalies in both dentitions. No differences were found in the average number of agenesis and morphological anomalies in the permanent teeth between both groups, but in the primary dentition group B presented a lower degree of incidence.

CONCLUSION

The presence of almost normal primary dentition (regarding to number), but with morphological anomalies, should lead to suspect their exacerbation in the permanent dentition.

摘要

目的

牙齿在形状和数量上的异常可能单独出现,也可能与其他表现相关。在无汗性外胚层发育不良中,这些异常出现得更为频繁且严重。作者检查了一组有类似牙齿异常但无其他外胚层或非外胚层体征的儿童。

方法

本研究对两组之间牙齿异常的异同进行了比较评估:A组为无汗性外胚层发育不良,B组为有类似牙齿表现但无牙齿外异常。

结果

在A组中,乳牙缺失的平均数量上颌为3.5颗,下颌为5.33颗;恒牙缺失的平均数量分别为5.4颗和5.8颗。在B组中,乳牙缺失的平均数量上颌为1.62颗,下颌为0.25颗,恒牙缺失的平均数量分别为4.0颗和4.25颗,且无固定的发生模式。对两组牙齿形态的研究显示,两副牙列中均有大量异常。两组恒牙在缺失平均数量和形态异常方面未发现差异,但在乳牙列中,B组的发病率较低。

结论

乳牙列(在数量方面)几乎正常但存在形态异常,这应引起对恒牙列中异常加重的怀疑。

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