Suzuki Yasuo
Tokai University School of Medicine, Department of Internal Medicine, Division of Rheumatology.
Clin Calcium. 2006 Nov;16(11):1834-42.
The effectiveness of drug therapy for the prevention or treatment of glucocorticoid-induced osteoporosis has been reported. Especially, the beneficial effects of bisphosphonates (etidoronate, alendronate, and risedronate) to prevent bone loss and fractures have been confirmed by the large-scale, multicenter, double-blind, randomized controlled trials in terms of both primary and secondary prevention. This article reviews the results of recent randomized prospective trials using bisphosphonates in glucocorticoid-induced osteoporosis.
已有报道称药物治疗对预防或治疗糖皮质激素性骨质疏松症有效。特别是，双膦酸盐类药物（依替膦酸盐、阿仑膦酸盐和利塞膦酸盐）在预防骨质流失和骨折方面的有益作用已在大规模、多中心、双盲、随机对照试验中得到了一级和二级预防方面的确证。本文综述了近期使用双膦酸盐治疗糖皮质激素性骨质疏松症的随机前瞻性试验结果。
