[在糖皮质激素诱导的骨质疏松症中激活维生素D3或双膦酸盐]
[Activate vitamin D3 or bisphosphonate in glucocorticoid-induced osteoporosis].
作者信息
Imanishi Yasuo, Nishizawa Yoshiki
机构信息
Osaka City University Graduate School of Medicine, Department of Metabolism, Endocrinology and Molecular Medicine.
出版信息
Clin Calcium. 2006 Nov;16(11):1844-50.
PMID:17079851
Abstract
Glucocorticoid therapy is associated with bone loss starting soon after the therapy is initiated and an increased risk of fracture. Activated forms of vitamin D(3), which are frequently prescribed for postmenopausal osteoporosis in Japan, are one of a useful agent to prevent glucocorticoid-induced osteoporosis. In this review, the effect of activate form vitamin D(3) is compared with plain vitamin D or bisphosphonate.
摘要
糖皮质激素治疗在开始后不久就会导致骨质流失，并增加骨折风险。活性形式的维生素D(3)在日本常用于绝经后骨质疏松症的治疗，是预防糖皮质激素诱导的骨质疏松症的有效药物之一。在本综述中，将活性形式的维生素D(3)与普通维生素D或双膦酸盐的效果进行了比较。
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