Bedford J J, Leader J P
Department of Physiology, University of Otago Medical School, Dunedin, New Zealand.
J Cardiovasc Pharmacol. 1990;16 Suppl 7:S24-6.
The effects of hyperosmotic stress under both acute and chronic conditions were investigated in two types of rat muscle tissue: cardiac and skeletal. Under acute conditions of a 4-h infusion, both types of muscle behaved as osmometers. However, under chronic hyperosmotic stress (several days), skeletal muscle behaved as predicted as an osmometer, but cardiac muscle did not. The levels of free amino acids in this tissue increased markedly--in particular, taurine. This phenomenon is discussed with respect to the capacity of this tissue for volume regulation.
在两种类型的大鼠肌肉组织（心肌和骨骼肌）中研究了急性和慢性条件下高渗应激的影响。在4小时输注的急性条件下，两种类型的肌肉都表现为渗透计。然而，在慢性高渗应激（数天）下，骨骼肌表现如预期的渗透计，但心肌并非如此。该组织中游离氨基酸水平显著增加，尤其是牛磺酸。就该组织的容量调节能力对这一现象进行了讨论。
