Laws Edward R, Vance Mary Lee, Jane John A
School of Medicine, University of Virginia, Charlottesville, VA 22908, USA.
Pituitary. 2006;9(4):313-5. doi: 10.1007/s11102-006-0411-x.
Thyrotropin (TSH) adenomas are uncommon tumors of the anterior pituitary. Clinically, they may present with hyperthyroidism, hypothyroidism, hypopituitarism, or visual loss. Proper diagnosis requires appropriate neuroendocrine evaluation. Although transsphenoidal surgery remains the first-line treatment, adjuvant medical therapy is frequently required for these often invasive tumors. Radiotherapy or radiosurgery should be considered for those patients with persistent TSH hypersecretion following surgery and medical therapy. The clinical evaluation and treatment algorithm for patients with TSH adenomas is discussed.
促甲状腺激素（TSH）腺瘤是垂体前叶少见的肿瘤。临床上，它们可能表现为甲状腺功能亢进、甲状腺功能减退、垂体功能减退或视力丧失。正确诊断需要进行适当的神经内分泌评估。尽管经蝶窦手术仍是一线治疗方法，但对于这些常具有侵袭性的肿瘤，通常还需要辅助药物治疗。对于手术后及药物治疗后仍持续TSH分泌过多的患者，应考虑放疗或放射外科治疗。本文讨论了TSH腺瘤患者的临床评估和治疗方案。
