Ricciardi R, Alavi K, Filice G A, Heilly S D, Spencer M P
Division of Colon & Rectal Surgery, University of Minnesota Medical School, Mayo Mail Code 450, 420 Delaware Street, SE, Minneapolis, Minnesota 55455, USA.
Dis Colon Rectum. 2007 Jan;50(1):118-21. doi: 10.1007/s10350-006-0743-7.
Isolated fungal infections of the perianal skin are rare and their diagnosis is frequently overlooked. We report a case of a 78-year-old male patient who presented with a friable, violaceous, papulopustular lesion, with heaped-up edges along the anal verge. Biopsy revealed unicellular yeast consistent with blastomycosis. The patient was treated with itraconazole with resolution of this lesion. An extensive MEDLINE literature review from 1958 to the present indicates that this is an uncommon manifestation of cutaneous blastomycosis. A summary of the medical literature is presented with a review of the characteristics, diagnosis, and management of blastomycosis.
肛周皮肤的孤立性真菌感染较为罕见,其诊断常常被忽视。我们报告一例78岁男性患者,其肛周出现一个质地脆、呈紫罗兰色的丘疹脓疱性损害,沿肛门边缘有隆起的边缘。活检显示为与芽生菌病相符的单细胞酵母。该患者接受伊曲康唑治疗后病变消退。对1958年至今的MEDLINE文献进行广泛回顾表明,这是皮肤芽生菌病的一种罕见表现。本文呈现了医学文献综述,并对芽生菌病的特征、诊断及治疗进行了回顾。