Meredith Paul, Sarna Tadeusz
Soft Condensed Matter Physics Group, School of Physical Sciences, University of Queensland, Brisbane, Australia.
Pigment Cell Res. 2006 Dec;19(6):572-94. doi: 10.1111/j.1600-0749.2006.00345.x.
In this article, we review the current state of knowledge concerning the physical and chemical properties of the eumelanin pigment. We examine properties related to its photoprotective functionality, and draw the crucial link between fundamental molecular structure and observable macroscopic behaviour. Where necessary, we also briefly review certain aspects of the pheomelanin literature to draw relevant comparison. A full understanding of melanin function, and indeed its role in retarding or promoting the disease state, can only be obtained through a full mapping of key structure-property relationships in the main pigment types. We are engaged in such an endeavor for the case of eumelanin.
在本文中,我们综述了有关真黑素色素物理和化学性质的当前知识状态。我们研究了与其光保护功能相关的性质,并揭示了基本分子结构与可观察到的宏观行为之间的关键联系。必要时,我们还简要回顾了褐黑素文献的某些方面以进行相关比较。只有通过全面描绘主要色素类型中关键的结构-性质关系,才能充分理解黑色素的功能及其在延缓或促进疾病状态中的作用。我们正在针对真黑素开展这样一项工作。