原发性皮肤弥漫性大B细胞淋巴瘤

Primary diffuse large B-cell lymphoma of the skin.

作者信息

Lazaris Andreas C, Nonni Aphrodite, Pathiaki Irene, Patsouris Efstratios

机构信息

Department of Pathology, Medical School, National and Kapodistrian University of Athens, Greece.

出版信息

Dermatol Online J. 2006 May 30;12(4):16.

PMID:17083871

Abstract

B-cell lymphomas of the skin represent a wide spectrum of disorders. We present the microscopic and immunohistochemical features of a primary cutaneous B-cell lymphoma and classify it either as a diffuse large B-cell lymphoma or an indolent follicle-center-cell lymphoma according to the updated REAL/WHO system and the EORTC classification respectively. The former system is widely recommended; nevertheless, the EORTC system is also worth considering when planning management, because most data on long-term outcomes are based on it and it is considered to offer remarkable prognostic information.

摘要

皮肤B细胞淋巴瘤代表了一系列广泛的疾病。我们展示了一例原发性皮肤B细胞淋巴瘤的显微镜及免疫组化特征，并分别根据更新后的REAL/WHO系统和欧洲癌症研究与治疗组织（EORTC）分类，将其归类为弥漫性大B细胞淋巴瘤或惰性滤泡中心细胞淋巴瘤。前一种系统被广泛推荐；然而，在制定治疗方案时，EORTC系统也值得考虑，因为大多数长期预后数据都基于该系统，并且它被认为能提供显著的预后信息。