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立体定向放射外科治疗表现为三叉神经痛的小脑幕硬脑膜动静脉畸形:病例报告

Tentorial dural arteriovenous malformation manifesting as trigeminal neuralgia treated by stereotactic radiosurgery: A case report.

作者信息

Matsushige Toshinori, Nakaoka Mitsuo, Ohta Keiji, Yahara Kaita, Okamoto Hisayo, Kurisu Kaoru

机构信息

Department of Neurosurgery, Matsue Red Cross Hospital, Matsue, Shimane 690-8506, Japan.

出版信息

Surg Neurol. 2006 Nov;66(5):519-23; discussion 523. doi: 10.1016/j.surneu.2006.01.022. Epub 2006 Jul 21.

DOI:10.1016/j.surneu.2006.01.022
PMID:17084201
Abstract

BACKGROUND

Tentorial dAVMs as a cause of trigeminal neuralgia are extremely rare. Consensus exists that radical treatment of such high-flow dAVMs should be considered because of their high risk of bleeding. The authors present a case of a 50-year-old man who presented with symptoms of tic douloureux caused by tentorial dAVM, which was treated successfully by SRS.

CASE DESCRIPTION

The patient consulted us with a 1-month history of harboring right trigeminal neuralgia. The cerebral angiography revealed a dAVM in the petrotentorial region and the MRI demonstrated a dilated petrosal venous varix compressing the root entry zone of the right trigeminal nerve. Gamma knife surgery was performed with a marginal dose of 18 Gy and a maximum dose of 30 Gy in a volume of 0.3 mL. The target point of the radiosurgery for this patient was a fistula identified by superselective angiography, enhanced computed tomography, and MRI. Follow-up MRI, 1 year after GKS, showed a thrombosed lesion, and the patient was able to end medication. There was no evidence of recurrence or adverse effects in the 3-year follow-up.

CONCLUSION

Stereotactic radiosurgery can play an effective role as a treatment modality for such unusual dAVMs.

摘要

背景

小脑幕动静脉畸形(dAVM)作为三叉神经痛的病因极为罕见。由于此类高流量dAVM出血风险高,因此对于其进行根治性治疗已达成共识。作者报告了一例50岁男性患者,其因小脑幕dAVM出现三叉神经痛症状,并通过立体定向放射外科治疗(SRS)成功治愈。

病例描述

该患者因右侧三叉神经痛1个月前来就诊。脑血管造影显示岩骨小脑幕区域存在一个dAVM,磁共振成像(MRI)显示扩张的岩骨静脉瘤压迫右侧三叉神经的神经根入区。采用伽玛刀手术,边缘剂量为18 Gy,最大剂量为30 Gy,照射体积为0.3 mL。该患者放射外科治疗的靶点是通过超选择性血管造影、增强计算机断层扫描和MRI确定的瘘口。伽玛刀手术(GKS)1年后的随访MRI显示病变血栓形成,患者能够停药。在3年的随访中未发现复发或不良反应的迹象。

结论

立体定向放射外科作为此类罕见dAVM的一种治疗方式可发挥有效作用。

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