鼻咽癌孤立性肝转移灶的手术切除：一例报告
Surgical resection of a solitary liver metastasis from nasopharyngeal carcinoma: a case report.
作者信息
Delis Spiros, Biliatis Ioannis, Bourli Antonia, Kapranos Nikolaos, Dervenis Christos
机构信息
Liver Surgical Unit, Agia Olga General Hospital of Athens, Agias Olgas 3-5 Street, Athens, Greece.
出版信息
Hepatobiliary Pancreat Dis Int. 2006 Nov;5(4):610-2.
BACKGROUND
Nasopharyngeal carcinoma (NPC) has a propensity to develop distant metastases at a high rate and with poor prognosis. Metastatic sites are usually multifocal and involve bones, lungs, liver and distant lymph nodes. Management of metastatic disease is essentially palliative and is based on chemotherapy.
METHODS
A 50-year-old man with a solitary liver metastasis from a newly diagnosed NPC was treated by segmentectomy. Prior to surgery, neoadjuvant chemotherapy followed by concurrent chemoradiotherapy was administered.
RESULTS
Complete remission of the primary disease was achieved, although the size of the hepatic lesion was increased. After resection of the liver metastasis, no signs of local or distant recurrence was noted during the 6-month follow up.
CONCLUSION
Although surgical treatment has a limited role in metastatic NPC, there are rare cases of localized disease with a reasonable outcome after resection.
背景
鼻咽癌（NPC）极易发生远处转移，转移率高且预后差。转移部位通常为多灶性，累及骨骼、肺、肝及远处淋巴结。转移性疾病的治疗主要是姑息性的，基于化疗。
方法
一名50岁男性，新诊断为鼻咽癌并伴有孤立性肝转移，接受了肝段切除术。术前先进行新辅助化疗，随后进行同步放化疗。
结果
尽管肝脏病变大小增加，但原发性疾病实现了完全缓解。肝转移灶切除后，在6个月的随访期间未发现局部或远处复发迹象。
结论
虽然手术治疗在转移性鼻咽癌中的作用有限，但仍有罕见的局限性疾病病例在切除后取得了合理的疗效。
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