胸腔积液和原发性支气管腺癌中的高淀粉酶活性。
High amylase activity in pleural fluid and primary bronchogenic adenocarcinoma.
作者信息
Devuyst O, Lambert M, Scheiff J M, Francart J
机构信息
Department of General Internal Medicine, St Luc University Hospital, Louvain Medical School, Brussels, Belgium.
出版信息
Eur Respir J. 1990 Nov;3(10):1217-20.
We report a case of primary bronchogenic adenocarcinoma, complicated by pleural effusion, in which very high pleural amylase activity was found, whilst serum amylase was normal. Isoamylase determination showed a salivary-type amylase. Concerning the origin of this enzyme, ultrastructural study of the malignant cells obtained from the pleural fluid suggested a local amylase synthesis. The pathophysiological significance of electron-dense granules found in these cells is also discussed.
我们报告一例原发性支气管腺癌合并胸腔积液的病例，该病例胸腔积液淀粉酶活性极高，而血清淀粉酶正常。同工淀粉酶测定显示为唾液型淀粉酶。关于这种酶的来源，对胸腔积液中获取的恶性细胞进行的超微结构研究提示存在局部淀粉酶合成。本文还讨论了在这些细胞中发现的电子致密颗粒的病理生理学意义。
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