Toyama Katsuhiro, Kimura Kazuhiro, Miyashita Minaho, Yanagisawa Rika, Nakata Koichiro
Department of Respiratory Medicine, Toho University School of Medicine.
Nihon Kokyuki Gakkai Zasshi. 2006 Oct;44(10):727-31.
The patient was a 59-year-old man who had been treated with continuous positive airway pressure for a diagnosis of obstructive sleep apnea syndrome. While cooking buckwheat noodles, the patient fell asleep with a frying pan on the fire. After four hours, he was awakened by the smell of burning as well as pharyngalgia, and visited this hospital. He was found to have hypoxia, and diagnostic imaging showed diffuse concentration increase with peripheral clear zones in bilateral lung fields, a typical finding of pulmonary edema. In view of the peculiar temporal course of his disease and inhalation of Teflon fumes immediately before its occurrence, he was considered to have polymer fume fever with non-cardiogenic pulmonary edema. After admission, he was treated with oxygen inhalation and diuretics, and experienced a rapid improvement of his general condition and findings on diagnostic imaging. In European countries and the United States, cases with a history of inhalation of Teflon fumes have been given a diagnosis of polymer fume fever. This case is of interest as it is apparently the first such disease reported in Japan.
该患者为一名59岁男性,因阻塞性睡眠呼吸暂停低通气综合征接受持续气道正压通气治疗。在煮荞麦面时,患者带着煎锅睡着了,火还开着。四个小时后,他被烧焦的气味和咽痛唤醒,随后前来本院就诊。检查发现他存在缺氧情况,诊断性影像学检查显示双侧肺野弥漫性密度增高,周边有清晰区域,这是肺水肿的典型表现。鉴于其疾病的特殊病程以及发病前立即吸入了特氟龙烟雾,考虑为聚合物烟雾热伴非心源性肺水肿。入院后,给予吸氧和利尿剂治疗,患者的一般状况及诊断性影像学检查结果迅速改善。在欧洲国家和美国,有吸入特氟龙烟雾病史的病例被诊断为聚合物烟雾热。该病例很有意思,因为这显然是日本首例此类疾病报告。