Enrique Ernesto, Cisteró-Bahíma Anna
Allergy Division, Hospital General de Castellón, Spain.
Curr Opin Allergy Clin Immunol. 2006 Dec;6(6):466-9. doi: 10.1097/01.all.0000246618.41871.a4.
Food allergy may be life threatening and its management continues to consist of avoiding relevant allergens and, in the case of accidental ingestion, initiation of appropriate emergency therapy. The aim of this article is to describe current treatment approaches and discuss attempts to use specific immunotherapy for food-allergy treatment.
A recent study reports the use of sublingual immunotherapy for hazelnut food allergy in hazelnut-allergic patients. A significant increase in tolerance to hazelnuts after sublingual immunotherapy as assessed by double-blind, placebo-controlled food challenge, and good tolerance to this treatment, have been observed.
The purpose of this review is to highlight the most promising novel approaches for treating food allergy beyond allergen avoidance. Some of these approaches alone, such as traditional Chinese herbal medicine, anti-immunoglobulin E therapy or sublingual immunotherapy for food allergy, or the combination of different approaches, would probably offer the best treatment option for food-allergic patients in the near future.
食物过敏可能危及生命，其治疗仍包括避免接触相关过敏原，以及在意外摄入的情况下启动适当的紧急治疗。本文旨在描述当前的治疗方法，并讨论使用特异性免疫疗法治疗食物过敏的尝试。
最近一项研究报告了在榛子过敏患者中使用舌下免疫疗法治疗榛子食物过敏。通过双盲、安慰剂对照食物激发试验评估，舌下免疫疗法后对榛子的耐受性显著增加，且该治疗耐受性良好。
本综述的目的是强调除了避免过敏原之外，治疗食物过敏最有前景的新方法。这些方法中的一些，如传统中药、抗免疫球蛋白E疗法或食物过敏的舌下免疫疗法，或者不同方法的组合，可能在不久的将来为食物过敏患者提供最佳治疗选择。
