Shmurun R I
Arkh Patol. 1975;37(8):68-71.
During the post-mortem examination of a 15-year patient who had died after the operation connected with incision of commissures a distorted form of the hypophysis was noted. Histological, histochemical and morphometric investigations showed that there was basophilic adenoma of adenohypophysis and prolapse of the tissue (beyond the borders of the adenoma) through a fistula against the background of changes characteristic of chronic diseases in childhood. Oxyphilic shift, moreover, was noted not only in the first zone of the adenohypophysis, but in other zones, as well as with a simultaneous increase in number of basophiles in I--III zones. Prolapse of the tissue, the latter being normal as far as the tumours growth was concerned, through the fistula took place at a considerable distance from the adenoma, which justifies the consideration of this process as a result of hyperplasia not connected with adenoma. Edges of the fistula bordering the prolapse, haemorrhages were to be seen.
在对一名15岁患者进行尸体解剖时，该患者在与联合切开相关的手术后死亡，发现垂体形态扭曲。组织学、组织化学和形态学研究表明，存在腺垂体嗜碱性腺瘤，并且在儿童慢性疾病特征性变化的背景下，组织（超出腺瘤边界）通过瘘管脱垂。此外，不仅在腺垂体的第一区，而且在其他区域都观察到嗜酸性转变，同时I - III区嗜碱性细胞数量增加。就肿瘤生长而言正常的组织通过瘘管在距腺瘤相当远的距离处发生脱垂，这证明将此过程视为与腺瘤无关的增生结果是合理的。在与脱垂相邻的瘘管边缘可见出血。
