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[1993年至2004年采用未改良迷宫手术治疗药物难治性或接近难治性心房颤动患者的长期良好结果;经验总结]

[Favourable long-term results using the unmodified maze procedure in patients with medication-refractory or nearly refractory atrial fibrillation; experience from 1993/'04].

作者信息

Geuzebroek G S C, Ballaux Ph K E W, Kelder J C, Brutel de la Rivière A, Defauw J J A M T, van N M

机构信息

St Antonius Ziekenhuis, Nieuwegein.

出版信息

Ned Tijdschr Geneeskd. 2006 Oct 21;150(42):2314-9.

PMID:17089550
Abstract

OBJECTIVE

To assess the short- and long-term results following the unmodified maze procedure in patients with medication-refractory or nearly refractory atrial fibrillation.

DESIGN

Retrospective.

METHODS

We retrospectively collected and analysed preoperatively in-hospital and follow-up data from patients with atrial fibrillation with or without structural heart disease who underwent the unmodified maze procedure in the St. Antonius hospital, Nieuwegein, the Netherlands.

RESULTS

In the 11-year period 1993-2004, 203 patients underwent the procedure: 139 underwent the maze procedure only and 64 underwent combined surgery for concomitant atrial fibrillation and structural heart disease. There were no in-hospital deaths. During a mean follow-up period of 4 years, 2 ofthe 203 patients died from cardiac causes; both had undergone combined surgery. With a mean follow-up period of 4 years, the rate of atrial fibrillation-free survival was 90% in patients with lone atrial fibrillation and 70% in patients with concomitant atrial fibrillation. For patients who had no recurrent atrial fibrillation 1 year after surgery, the risk of recurrence after 4 years was small (odds ratio: 9.56). Risk factors for recurrence included a large left atrium and a long duration of atrial fibrillation (more than 5 years).

CONCLUSION

The maze procedure was a successful surgical intervention for patients with atrial fibrillation, both in the short and long term. This procedure can be considered when medication and electrical cardioversion are ineffective.

摘要

目的

评估未改良迷宫手术治疗药物难治性或接近难治性心房颤动患者的短期和长期疗效。

设计

回顾性研究。

方法

我们回顾性收集并分析了在荷兰尼乌韦根圣安东尼医院接受未改良迷宫手术的有或无结构性心脏病的心房颤动患者的术前住院和随访数据。

结果

在1993年至2004年的11年期间,203例患者接受了该手术:139例仅接受了迷宫手术,64例因合并心房颤动和结构性心脏病接受了联合手术。无住院死亡病例。在平均4年的随访期内,203例患者中有2例死于心脏原因;这2例均接受了联合手术。平均随访4年,孤立性心房颤动患者无房颤生存率为90%,合并心房颤动患者为70%。对于术后1年无房颤复发的患者,4年后复发风险较小(优势比:9.56)。复发的危险因素包括左心房增大和房颤持续时间长(超过5年)。

结论

迷宫手术对心房颤动患者而言,无论短期还是长期都是一种成功的外科干预措施。当药物治疗和电复律无效时可考虑采用该手术。

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