Dong Vy M, Fiedler Dorothea, Carl Barbara, Bergman Robert G, Raymond Kenneth N
Department of Chemistry, University of California, Berkeley, California 94720-1460, USA.
J Am Chem Soc. 2006 Nov 15;128(45):14464-5. doi: 10.1021/ja0657915.
Iminium ions are known to exist only transiently in aqueous solution due to their high reactivity toward hydrolysis. In this communication, we report on the generation and stabilization of iminium ions in aqueous solution via molecular encapsulation using a K12Ga4L6 host. Our studies revealed that tetrahedral host 1 can encapsulate a variety of iminium cations in a molecular recognition process that is selective based on the charge, hydrophobicity, size, and shape of the guest.
由于亚胺离子对水解具有高反应活性，已知其仅在水溶液中短暂存在。在本通讯中，我们报道了通过使用K12Ga4L6主体进行分子包封，在水溶液中生成并稳定亚胺离子。我们的研究表明，四面体主体1可以在基于客体的电荷、疏水性、大小和形状具有选择性的分子识别过程中包封多种亚胺阳离子。
