Kohl Shane K, Aoun Patricia
Department of Pathology and Microbiology, University of Nebraska Medical Center, Omaha 68198-3135, USA.
Arch Pathol Lab Med. 2006 Oct;130(10):1570-4. doi: 10.5858/2006-130-1570-GSOTSI.
Granulocytic sarcoma is an extramedullary tumor of myeloblasts and/or immature myeloid cells, which can develop at any anatomic site and is often a forerunner to the development of acute myelogenous leukemia. Granulocytic sarcoma of the gastrointestinal tract most frequently involves the small intestine and most often presents with abdominal pain and obstruction. Pathologists must consider granulocytic sarcoma in any mass of unknown origin with a diffusely infiltrating population of tumor cells, as the diagnosis is often initially unrecognized, especially in nonleukemic patients. Multiple ancillary modalities are available to assist pathologists in making the correct diagnosis so that appropriate therapy can be initiated.
粒细胞肉瘤是一种由成髓细胞和/或未成熟髓样细胞构成的髓外肿瘤，可发生于任何解剖部位，常为急性髓系白血病发生的先兆。胃肠道粒细胞肉瘤最常累及小肠，且最常表现为腹痛和梗阻。对于任何起源不明且有弥漫性浸润肿瘤细胞群的肿块，病理学家都必须考虑粒细胞肉瘤，因为该诊断最初往往未被识别，尤其是在非白血病患者中。有多种辅助检查方法可帮助病理学家做出正确诊断，从而启动适当的治疗。
