Lee Jerome, McPherson Mary Lynn
Walgreens Pharmacy, Baltimore, MD 21201, USA.
Am J Health Syst Pharm. 2006 Nov 15;63(22):2235-9. doi: 10.2146/ajhp060143.
The value of pharmaceutical care recommendations made by consultant pharmacists and the outcomes of these recommendations were studied.
The study was conducted at three hospice programs, and the investigators were consultant pharmacists who shared the responsibility of providing drug therapy recommendations to the three programs. A literature search was conducted to determine if any tools had been developed to evaluate recommendations made by pharmacists in clinical practice settings. One tool was identified and adapted for use in a hospice clinical setting. Drug-related problems (DRPs) (n = 98), clinical interventions (n = 87), and outcomes data were collected by two hospice consultant pharmacists and evaluated by a panel of experts using the assessment tool.
Ninety-eight interventions were collected and evaluated. Eighty-seven of the 98 interventions were classified as clinical interventions with specific therapeutic goals established. Of these 87 interventions, 73 (84%) were accepted by the prescriber and 56 (77%) out of the 73 helped achieve the therapeutic goals. An additional 6 (8%) interventions partially achieved the therapeutic goals. Over 75% of all of the pharmacists' recommendations achieved their intended therapeutic effect, which resulted in better management of the patients' physical symptoms. None of the accepted recommendations resulted in the patient coming to harm or having an adverse effect. Overall agreement between raters for severity and value was moderately high, 60-70% and 63-80%, respectively. Kappa scores were low.
Hospice-based clinical pharmacists influenced patient outcomes positively by identifying DRPs and recommending appropriate drug therapy.
研究临床药师提出的药学服务建议的价值及其建议结果。
该研究在三个临终关怀项目中开展,研究者为临床药师,他们共同负责为这三个项目提供药物治疗建议。进行文献检索以确定是否已开发出任何工具来评估临床实践中药师提出的建议。确定了一种工具并对其进行调整以用于临终关怀临床环境。两名临终关怀临床药师收集了药物相关问题(DRP,n = 98)、临床干预措施(n = 87)及结果数据,并由一个专家小组使用评估工具进行评估。
收集并评估了98项干预措施。98项干预措施中的87项被归类为具有明确治疗目标的临床干预措施。在这87项干预措施中,73项(84%)被开处方者接受,73项中的56项(77%)有助于实现治疗目标。另外6项(8%)干预措施部分实现了治疗目标。所有药师建议中超过75%达到了预期治疗效果,从而使患者身体症状得到更好的管理。所有被接受的建议均未导致患者受到伤害或产生不良反应。评分者之间在严重程度和价值方面的总体一致性较高,分别为60 - 70%和63 - 80%。kappa值较低。
基于临终关怀的临床药师通过识别药物相关问题并推荐适当的药物治疗,对患者结局产生了积极影响。