以肠道假性梗阻为首发表现的胸腺瘤

Intestinal pseudo-obstruction as initial presentation of thymoma.

作者信息

Musthafa C P, Moosa Ahsan, Chandrashekharan P A, Nandakumar R, Narayanan A V, Balakrishnan V

机构信息

Department of Gastroenterology, Amrita Institute of Medical Sciences, Amrita Lane, Elamakkara P O, Cochin 682 026, India.

出版信息

Indian J Gastroenterol. 2006 Sep-Oct;25(5):264-5.

PMID:17090854

Abstract

A 45-year-old-man presented with severe vomiting, constipation, abdominal distention and bilateral ocular abductor palsy. Evaluation revealed diffuse autonomic dysfunction characterized by intestinal pseudo-obstruction, xerophthalmia, xerostomia, postural hypotension, erectile dysfunction and loss of sinus arrhythmia. Paraneoplastic work-up revealed thymoma. Most symptoms resolved after surgical removal of the thymoma. Six weeks later he developed worsening of external ophthalmoparesis with ptosis, responding to acetylcholinesterase inhibitor, confirming myasthenia gravis.

摘要

一名45岁男性出现严重呕吐、便秘、腹胀及双侧眼球外展肌麻痹。检查发现弥漫性自主神经功能障碍，其特征为肠道假性梗阻、干眼症、口干、体位性低血压、勃起功能障碍及窦性心律不齐消失。副肿瘤相关检查发现胸腺瘤。手术切除胸腺瘤后，多数症状缓解。六周后，他出现伴有上睑下垂的眼球外肌麻痹加重，对乙酰胆碱酯酶抑制剂有反应，确诊为重症肌无力。