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胸腺瘤、重症肌无力及其他副肿瘤综合征。

Thymoma, myasthenia gravis, and other paraneoplastic syndromes.

作者信息

Tormoehlen Laura M, Pascuzzi Robert M

机构信息

Department of Neurology, Indiana University School of Medicine, Emerson Hall Room 125, 545 Barnhill Drive, Indianapolis, IN 46202, USA.

出版信息

Hematol Oncol Clin North Am. 2008 Jun;22(3):509-26. doi: 10.1016/j.hoc.2008.03.004.

DOI:10.1016/j.hoc.2008.03.004
PMID:18514130
Abstract

The relationship between myasthenia gravis and thymic pathology, including thymoma, is well known. Approximately 10% to 15% of patients who have myasthenia gravis are observed to have a thymoma. Myasthenia gravis may be considered as the most common of the paraneoplastic syndromes in patients who have thymoma. This article summarizes the clinical aspects of myasthenia gravis, followed by a review of the less often recognized paraneoplastic disorders noted to occur in patients who have thymoma.

摘要

重症肌无力与胸腺病理(包括胸腺瘤)之间的关系已广为人知。约10%至15%的重症肌无力患者被观察到患有胸腺瘤。重症肌无力可被视为胸腺瘤患者中最常见的副肿瘤综合征。本文总结了重症肌无力的临床特点,随后回顾了胸腺瘤患者中较少被认识到的副肿瘤性疾病。

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Clin Case Rep. 2024 Jun 14;12(6):e9065. doi: 10.1002/ccr3.9065. eCollection 2024 Jun.
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Autoimmunity in thymic epithelial tumors: a not yet clarified pathologic paradigm associated with several unmet clinical needs.胸腺癌中的自身免疫:一个尚未阐明的病理模式,与多个未满足的临床需求相关。
Front Immunol. 2024 Apr 2;15:1288045. doi: 10.3389/fimmu.2024.1288045. eCollection 2024.
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