Brar Gagandeep S, Bandyopadhyay Supratik, Kaushik Sushmita, Raj Surishti
Department of Ophthalmology, Postgraduate Institute of Medical Education and Research, Chandigarh, Punjab, India.
Indian J Ophthalmol. 2006 Dec;54(4):257-60. doi: 10.4103/0301-4738.27951.
To analyse results of full time occlusion therapy for amblyopia in children older than 6 years.
This was a retrospective consecutive case series analysis of children treated for amblyopia at a tertiary care center. All children received full time occlusion (FTO) for the dominant eye.
Eighty-eight children older than 6 years at the time of initiation of therapy were included. Age at initiation of therapy ranged from 6 to 20 years (9.45 +/- 3.11 years). Forty-two children (47.7%) had strabismic amblyopia, 37 (42.0%) had anisometropic amblyopia and 9 (10.2%) had a combination of strabismic and anisometropic amblyopia. Eighty out of 88 eyes (90.0%) had improvement in visual acuity following FTO. Visual acuity (VA) improved from 0.82 +/- 0.34 at presentation to 0.42 +/- 0.34 (P < 0.001) after FTO. In children with strabismic amblyopia, VA improved from 0.81 +/- 0.42 to 0.42 +/- 0.39 (P <0.001). In children with anisometropic amblyopia, visual acuity of the amblyopic eye improved fron 0.82 +/- 0.24 to 0.36 +/- 0.29 (P< 0.001) following FTO. Out of 13 children older than 12 years, only 6 children (46.1%) had improvement in VA. Mean follow-up after complete stoppage of occlusion was 8.37 +/- 1.78 months.
Occlusion therapy yields favorable results in strabismic and/or anisometropic amblyopia, even when initiated for the first time after 6 years of age. After 12 years of age, some children may still respond to occlusion of the dominant eye.
分析6岁以上儿童弱视全时遮盖疗法的效果。
这是对一家三级医疗中心接受弱视治疗的儿童进行的回顾性连续病例系列分析。所有儿童均接受对优势眼的全时遮盖（FTO）。
纳入了88名开始治疗时年龄大于6岁的儿童。开始治疗时的年龄范围为6至20岁（9.45±3.11岁）。42名儿童（47.7%）患有斜视性弱视，37名（42.0%）患有屈光参差性弱视，9名（10.2%）患有斜视性和屈光参差性弱视的组合。88只眼中有80只（90.0%）在FTO后视力得到改善。视力（VA）从就诊时的0.82±0.34提高到FTO后的0.42±0.34（P<0.001）。在患有斜视性弱视的儿童中，VA从0.81±0.42提高到0.42±0.39（P<0.001）。在患有屈光参差性弱视的儿童中，弱视眼的视力在FTO后从0.82±0.24提高到0.36±0.29（P<0.001）。在13名12岁以上的儿童中，只有6名儿童（46.1%）视力得到改善。完全停止遮盖后的平均随访时间为8.37±1.78个月。
遮盖疗法在斜视性和/或屈光参差性弱视中产生了良好的效果，即使在6岁以后首次开始治疗也是如此。12岁以后，一些儿童可能仍然对遮盖优势眼有反应。
