Adukauskiene Dalia, Kinderyte Aida, Tarasevicius Rimantas, Vitkauskiene Astra
Clinic of Intensive Therapy, Kaunas University of Medicine, A. Mickeviciaus 9, 44307 Kaunas, Lithuania.
Medicina (Kaunas). 2006;42(10):805-9.
To determine the incidence and variety of microorganisms of positive urine culture in patients of intensive care units of Kaunas University of Medicine Hospital and to estimate the risk factors for colonization, development of urinary tract infection, and outcome during the period of 2003-2004.
We retrospectively reviewed patients with a positive urine culture with or without clinical symptoms of urinary tract infection admitted to an intensive care unit.
The growth of microorganisms was determined in urine of 82 (3.9%) patients: urinary tract infection in 64 (78%) and colonization in 18 (22%) patients. Among pathogens of urinary tract infection rods predominated significantly (p<0.05). No significant difference was found among colonizing microorganisms (p>0.05). E. coli in urine culture was obtained exclusively in cases of urinary tract infection. All patients with a positive urine culture had catheterized urinary bladder (p<0.05). No influence of age, sex, or duration of catheterization alone on the occurrence of urinary tract infection, colonization, or outcome was found (p>0.05). In cases of the same sex, age, and underlying disease of the patients, the risk of urinary tract infection with every day of catheterization significantly increased by 21.7% (p<0.05). Among patients with lethal outcome there was a significant prevalence of rods in urine culture (p<0.05). In survivors, no significant pathogen was detected in urine culture (p>0.05). In cases of the same sex, age, underlying disease, and duration of catheterization, the development of urinary tract infection significantly increased the risk of lethal outcome by 5.5 times (p<0.05).
Positive urine culture was found in 3.9% of patients, three-quarters of them were due to urinary tract infection. Rods were the predominant pathogens in urinary tract infection. E. coli in urinary tract always resulted in urinary tract infection. Catheterization of urinary bladder resulted in urinary tract infection or colonization. Each day of urinary bladder catheterization increased the risk of development of urinary tract infection by 21.7%. Rods in urine culture were associated with lethal outcome. Development of urinary tract infection increased the risk of lethal outcome 5.5 times.
确定考纳斯医科大学医院重症监护病房患者尿培养阳性的微生物发生率及种类，并评估2003 - 2004年期间定植、尿路感染发生及转归的危险因素。
我们回顾性分析了入住重症监护病房且尿培养阳性、有或无尿路感染临床症状的患者。
82例（3.9%）患者的尿液中检测到微生物生长：64例（78%）为尿路感染，18例（22%）为定植。尿路感染病原体中杆菌占显著优势（p<0.05）。定植微生物之间未发现显著差异（p>0.05）。尿培养中仅在尿路感染病例中分离出大肠杆菌。所有尿培养阳性患者均有导尿史（p<0.05）。未发现年龄、性别或单独的导尿时间对尿路感染、定植或转归的发生有影响（p>0.05）。在性别、年龄和基础疾病相同的患者中，导尿每一天尿路感染的风险显著增加21.7%（p<0.05）。在死亡患者中，尿培养中杆菌显著占优势（p<0.05）。在存活患者中，尿培养未检测到显著的病原体（p>0.05）。在性别、年龄、基础疾病和导尿时间相同的情况下，尿路感染的发生使死亡风险显著增加5.5倍（p<0.05）。
3.9%的患者尿培养阳性，其中四分之三是由尿路感染引起。杆菌是尿路感染的主要病原体。尿路中的大肠杆菌总是导致尿路感染。导尿会导致尿路感染或定植。导尿每一天尿路感染发生的风险增加21.7%。尿培养中的杆菌与死亡结局相关。尿路感染的发生使死亡风险增加5.5倍。
