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脊髓硬膜内髓外海绵状血管瘤:病例报告及文献综述

Spinal intradural extramedullary cavernous angioma: case report and review of the literature.

作者信息

Er U, Yigitkanli K, Simsek S, Adabag A, Bavbek M

机构信息

Department of Neurosurgery, Diskapi Yildirim Beyazid Training and Research Hospital, Ankara, Turkey.

出版信息

Spinal Cord. 2007 Sep;45(9):632-6. doi: 10.1038/sj.sc.3101990. Epub 2006 Nov 7.

Abstract

STUDY DESIGN

Case report and review of the literature.

OBJECTIVE

To report an unusual case of a spinal intradural extramedullary cavernous angioma (CA), located at the cauda equina, and to compare it with the previously published 22 surgically treated cases in the literature.

SETTING

Ankara, Turkey.

METHOD

A 67-year-old man presented with a 4-month history of back pain and sciatica and a 4-week history of progressive lower extremity paresthesia, difficulty walking, and loss of bladder and bowel sphincter control. Neurological examination revealed bilateral hypoesthesia below the T12 dermatome with spastic paraparesis. Magnetic resonance imaging (MRI) of the cauda equina revealed a heterogeneous enhancing intradural extramedullary mass obliterating the spinal canal and expanding the spinal cord. T12 laminectomy and total tumor removal were performed without additional neurological deficit. Pathological examination confirmed the diagnosis of a CA.

RESULT

The patient's neurological status improved during postoperative recovery. He was ambulatory without assistance and regained full sphincter control on the eighth postoperative week.

CONCLUSION

CAs of the spinal cord are extremely rare lesions. Typically, they present with low back pain and sciatica, neurological deficits, or as a subarachnoid hemorrhage. These lesions have characteristic features on MRI and should be considered in the differential diagnosis of intradural spinal lesions. Following a thorough literature review of reported cases, the authors propose that for patients presenting with severe preoperative neurological signs, immediate microsurgical tumor excision or decompression increases the chance of neurological improvement.

摘要

研究设计

病例报告及文献综述。

目的

报告一例罕见的位于马尾的脊髓硬膜内髓外海绵状血管瘤(CA)病例,并与文献中此前报道的22例接受手术治疗的病例进行比较。

地点

土耳其安卡拉。

方法

一名67岁男性,有4个月的背痛和坐骨神经痛病史,以及4周的进行性下肢感觉异常、行走困难和膀胱及肠道括约肌控制丧失病史。神经系统检查显示T12皮节以下双侧感觉减退伴痉挛性轻截瘫。马尾磁共振成像(MRI)显示硬膜内髓外有一不均匀强化肿块,阻塞椎管并使脊髓增粗。行T12椎板切除术并完整切除肿瘤,未出现额外的神经功能缺损。病理检查确诊为CA。

结果

患者术后恢复过程中神经功能状态改善。术后第8周,他无需辅助即可行走,并恢复了完全的括约肌控制。

结论

脊髓CA是极其罕见的病变。通常表现为腰痛和坐骨神经痛、神经功能缺损或蛛网膜下腔出血。这些病变在MRI上有特征性表现,在硬膜内脊髓病变的鉴别诊断中应予以考虑。在对报道病例进行全面文献综述后,作者提出,对于术前有严重神经体征的患者,立即进行显微手术切除肿瘤或减压可增加神经功能改善的机会。

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