Coppens Joris E, Franssen Luuk, van den Berg Thomas J T P
Netherlands Ophthalmic Research Institute, Meibergdreef 47 1105BA, Amsterdam, Netherlands.
J Biomed Opt. 2006 Sep-Oct;11(5):054010. doi: 10.1117/1.2357731.
Recently the psychophysical compensation comparison method was developed for routine measurement of retinal stray light. The subject's responses to a series of two-alternative-forced-choice trials are analyzed using a maximum-likelihood (ML) approach assuming some fixed shape for the psychometric function (PF). This study evaluates the reliability of the method using Monte-Carlo simulations. Various sampling strategies were investigated, including the two-phase sampling strategy that is used in a commercially available instrument. Results are given for the effective dynamic range and measurement accuracy. The effect of a mismatch of the shape of the PF of an observer and the fixed shape used in the ML analysis was analyzed. Main outcomes are that the two-phase sampling scheme gives good precision (Standard deviation = 0.07 logarithmic units on average) for estimation of the stray light value. Bias is virtually zero. Furthermore, a reliability index was derived from the responses and found to be effective.
最近，心理物理学补偿比较法被开发用于视网膜杂散光的常规测量。假设心理测量函数（PF）具有某种固定形状，使用最大似然（ML）方法分析受试者对一系列二选一强制选择试验的反应。本研究使用蒙特卡罗模拟评估该方法的可靠性。研究了各种采样策略，包括在商用仪器中使用的两阶段采样策略。给出了有效动态范围和测量精度的结果。分析了观察者PF形状与ML分析中使用的固定形状不匹配的影响。主要结果是，两阶段采样方案在估计杂散光值时具有良好的精度（平均标准差 = 0.07对数单位）。偏差几乎为零。此外，从反应中得出了一个可靠性指标，发现它是有效的。
