Van Heuverswyn Fran, Li Yingying, Neel Cecile, Bailes Elizabeth, Keele Brandon F, Liu Weimin, Loul Severin, Butel Christelle, Liegeois Florian, Bienvenue Yanga, Ngolle Eitel Mpoudi, Sharp Paul M, Shaw George M, Delaporte Eric, Hahn Beatrice H, Peeters Martine
UMR145, Institut de Recherche pour le Développement and Department of International Health, University of Montpellier 1, 34394 Montpellier Cedex 5, France.
Nature. 2006 Nov 9;444(7116):164. doi: 10.1038/444164a.
Chimpanzees (Pan troglodytes troglodytes) from west central Africa are recognized as the reservoir of simian immunodeficiency viruses (SIVcpzPtt) that have crossed at least twice to humans: this resulted in the AIDS pandemic (from human immunodeficiency virus HIV-1 group M) in one instance and infection of just a few individuals in Cameroon (by HIV-1 group N) in another. A third HIV-1 lineage (group O) from west central Africa also falls within the SIVcpzPtt radiation, but the primate reservoir of this virus has not been identified. Here we report the discovery of HIV-1 group O-like viruses in wild gorillas.
来自非洲中西部的黑猩猩（Pan troglodytes troglodytes）被认为是猿猴免疫缺陷病毒（SIVcpzPtt）的宿主，该病毒至少两次传播给人类：一次导致了艾滋病大流行（源于人类免疫缺陷病毒HIV-1 M组），另一次在喀麦隆仅感染了少数个体（由HIV-1 N组引起）。来自非洲中西部的第三种HIV-1谱系（O组）也属于SIVcpzPtt辐射范围，但该病毒的灵长类宿主尚未确定。在此，我们报告在野生大猩猩中发现了HIV-1 O组样病毒。
