与单纯输血相比，换血疗法用于首次显性卒中时，后续卒中风险较低：一项对137例镰状细胞贫血患儿的回顾性队列研究。
Exchange blood transfusion compared with simple transfusion for first overt stroke is associated with a lower risk of subsequent stroke: a retrospective cohort study of 137 children with sickle cell anemia.
作者信息
Hulbert Monica L, Scothorn Douglas J, Panepinto Julie A, Scott J Paul, Buchanan George R, Sarnaik Sharada, Fallon Robert, Chu Jen-Yih, Wang Winfred, Casella James F, Resar Linda, Berman Brian, Adamkiewicz Thomas, Hsu Lewis L, Smith-Whitley Kimberly, Mahoney Donald, Woods Gerald, Watanabe Masayo, DeBaun Michael R
机构信息
Washington University School of Medicine, St. Louis, MO 63108, USA.
出版信息
J Pediatr. 2006 Nov;149(5):710-2. doi: 10.1016/j.jpeds.2006.06.037.
A retrospective cohort study of children with sickle cell anemia (SCA) and strokes was used to test the hypothesis that exchange transfusion at the time of stroke presentation more effectively prevents second strokes than does simple transfusion. Children receiving simple transfusion had a 5-fold greater relative risk (95% confidence interval = 1.3 to 18.6) of second stroke than those receiving exchange transfusion.
一项针对镰状细胞贫血（SCA）患儿及中风情况的回顾性队列研究，旨在检验以下假设：与单纯输血相比，在中风发作时进行换血疗法能更有效地预防二次中风。接受单纯输血的儿童发生二次中风的相对风险比接受换血疗法的儿童高5倍（95%置信区间 = 1.3至18.6）。
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