Labrosse H, Vantard N, Garcia K, Leboucher G, Charpiat B
Service Pharmaceutique, Hôpital de la Croix Rousse, 103, grande rue de la Croix Rousse, F 69317 Lyon Cedex 04.
Ann Pharm Fr. 2006 Sep;64(5):344-9. doi: 10.1016/s0003-4509(06)75327-5.
The report published by the French Agency for the Medical Safety of Health Products in 2001 estimated the number of hospital admissions in France for hemorrhagic accidents caused by oral anticoagulants (OA) to be 17,000. For this reason, we have set up pharmaceutical counselling for hospitalized patients treated with OA. The object of this article is to describe this therapeutic education program and to present the level of knowledge that patients have of their OA treatment. Among 68 patients treated prior to their admission, 87% knew the name of the OA, 86% the role of this treatment, 80% the dosing schedule, 57% what to do if a dose had been forgotten, 34% the signs of overdose, 48% the signs of and risks associated with not following the treatment schedule, 94% the advantage of biological follow-up and 68% the principal combinations of drugs that should be avoided. Among 118 patients whose treatment was begun during hospitalization, the level of knowledge for each item were respectively: 41%, 61%, 38%, 37%, 19%, 23%, 34% and 24% at the time of counselling. Newly treated patients acquired their knowledge from contact with nurses. The least known items were the symptoms and risks associated with overdosing or underdosing. This knowledge is therefore fragmentary and does not guarantee the patients' safety, which justifies the proposition of this type of counselling to such hospitalized patients.
法国卫生产品医疗安全局2001年发布的报告估计，法国因口服抗凝剂（OA）导致出血事故而住院的人数为17000人。因此，我们为接受OA治疗的住院患者设立了药学咨询服务。本文的目的是描述这一治疗教育项目，并介绍患者对其OA治疗的了解程度。在68名入院前接受治疗的患者中，87%知道OA的名称，86%知道这种治疗的作用，80%知道给药时间表，57%知道如果忘记服药该怎么办，34%知道过量用药的迹象，48%知道不遵守治疗时间表的迹象和相关风险，94%知道进行生物学监测的好处，68%知道应避免的主要药物组合。在118名住院期间开始治疗的患者中，咨询时各项的知晓程度分别为：41%、61%、38%、37%、19%、23%、34%和24%。新接受治疗的患者通过与护士接触获取知识。最不为人所知的项目是与用药过量或用药不足相关的症状和风险。因此，这些知识是零碎的，不能保证患者的安全，这就证明了向这类住院患者提供此类咨询的合理性。
