Gum Amber M, Areán Patricia A, Bostrom Alan
Department of Aging and Mental Health, Louis de la Parte Florida Mental Health Institute, University of South Florida, 13301 Bruce B. Downs Boulevard, MHC 1400, Tampa, FL 33612, USA.
Int J Geriatr Psychiatry. 2007 Feb;22(2):124-30. doi: 10.1002/gps.1702.
This study examined the influence of comorbid anxiety and personality disorders on depression treatment response in 67 low-income older adults.
Participants were randomized to clinical case management, cognitive-behavioral group therapy, or both for 6 months. Outcomes were assessed at baseline, post-treatment, and 6 and 12 months after treatment.
Dropout and depression diagnoses were similar across groups. Participants with comorbidity had more depressive and anxiety symptoms at most time points; degree of improvement did not differ significantly. Of participants with personality disorder, none met criteria at post-treatment (three relapsed by 12-month follow-up).
Findings suggest depressed low-income elders with anxiety or personality disorders can be retained and benefit from depression treatment, but may require additional interventions to achieve similar levels of depressive symptoms.
本研究调查了67名低收入老年人中，共病焦虑和人格障碍对抑郁症治疗反应的影响。
参与者被随机分配到临床病例管理组、认知行为团体治疗组或两组同时参与，为期6个月。在基线、治疗后、治疗后6个月和12个月时评估结果。
各组的退出率和抑郁症诊断情况相似。共病患者在大多数时间点有更多的抑郁和焦虑症状；改善程度无显著差异。人格障碍患者中，治疗后无人符合标准（到12个月随访时有3人复发）。
研究结果表明，患有焦虑或人格障碍的低收入抑郁症老年人可以坚持接受抑郁症治疗并从中受益，但可能需要额外的干预措施才能达到类似的抑郁症状缓解水平。
