Lin Jiang, Chen Bin, Wang Jian-hua
Department of Radiology, Shanghai Zhongshan Hospital, Shanghai Medical College, Fudan University, Shanghai 200032, China.
Chin Med J (Engl). 2006 Nov 5;119(21):1772-8.
With the development of magnetic resonance (MR) technologies, whole-body 3D contrast-enhanced MR angiography (3D CE MRA) has become possible. The purpose of this study was to introduce and evaluate this technique in demonstration of various systemic arterial diseases.
Thirty-seven patients underwent whole-body 3D CE MRA using a 1.5T MR imager. The patients included were with clinically documented or suspected peripheral arterial occlusive disease (PAOD, n = 19), Takayasu arteritis (n = 8), polyarteritis nodosa (n = 1), Type B dissection (n = 4) and thoracic and/or abdominal aneurysm (n = 5). Sixty-eight surface coil elements were employed to encompass the whole body. Four 3D CE MRA stations were acquired successively through automatic table moving. A total scan range of 188 cm, covering the arterial tree from carotid artery to trifurcation vessels, was acquired. Overall image quality of each arterial segment and venous overlay were assessed and rated. The depiction of various systemic arterial diseases was evaluated and compared with other imaging modalities if available, including digital subtraction angiography (DSA), CT angiography, dedicated mono-station MRA.
Whole-body 3D CE MRA was well tolerated by all patients. It yielded a detailed display of the arterial system with a short examination time. The image quality was considered diagnostic in 99.3% of the arterial segments. The remaining 0.7% of the arterial segments were considered non-diagnostic. In 7 of 19 patients with PAOD, whole-body MRA showed additional vascular narrowing apart from peripheral arterial disease. In 9 patients with vasculitis, whole-body MRA depicted luminal irregularity, narrowing or occlusion, aneurysm and collateral circulation involving multiple vascular segments. Whole-body MRA also clearly revealed the severity and extent of dissection and aortic aneurysm. In 20 cases the vascular pathologies demonstrated on whole body MRA were confirmed by other imaging investigations.
The whole-body MRA technique was non-invasive, quick and easy to perform. It was valuable for a comprehensive evaluation of vascular involvement of various systemic arterial diseases.
随着磁共振（MR）技术的发展，全身三维对比增强磁共振血管造影（3D CE MRA）已成为可能。本研究的目的是介绍并评估该技术在各种系统性动脉疾病诊断中的应用。
37例患者使用1.5T MR成像仪进行全身3D CE MRA检查。纳入患者包括临床记录或怀疑患有外周动脉闭塞性疾病（PAOD，n = 19）、大动脉炎（n = 8）、结节性多动脉炎（n = 1）、B型主动脉夹层（n = 4）以及胸和/或腹主动脉瘤（n = 5）。采用68个表面线圈单元覆盖全身。通过自动床移动连续采集4个3D CE MRA部位。共获得188 cm的扫描范围，覆盖从颈动脉到分叉血管的动脉树。评估并分级每个动脉节段的整体图像质量以及静脉重叠情况。评估各种系统性动脉疾病的显示情况，并与其他可用的成像方式进行比较，包括数字减影血管造影（DSA）、CT血管造影、专用单部位MRA。
所有患者对全身3D CE MRA耐受性良好。该技术在短时间检查内即可详细显示动脉系统。99.3%的动脉节段图像质量被认为可用于诊断。其余0.7%的动脉节段被认为无法诊断。在19例PAOD患者中，有7例全身MRA显示除外周动脉疾病外还存在其他血管狭窄。在9例血管炎患者中，全身MRA显示管腔不规则、狭窄或闭塞、动脉瘤以及涉及多个血管节段的侧支循环。全身MRA还清晰显示了主动脉夹层和主动脉瘤的严重程度及范围。在20例患者中，全身MRA显示的血管病变经其他影像学检查得到证实。
全身MRA技术具有无创、快速且易于操作的特点。对于全面评估各种系统性动脉疾病的血管受累情况具有重要价值。
