Berg Frank, Bangard Christopher, Bovenschulte Henning, Nijenhuis Marco, Hellmich Martin, Lackner Klaus, Gossmann Axel
Department of Radiology, University of Cologne, Kerpener Str. 62, 50924 Cologne, Germany.
Eur J Radiol. 2009 Apr;70(1):170-6. doi: 10.1016/j.ejrad.2007.12.008. Epub 2008 Feb 19.
The objective of this study was to describe contrast-enhanced magnetic resonance angiography (MRA) of the lower extremities at 3.0 T system for assessment of high resolution images in patients with peripheral arterial occlusive disease (PAOD).
21 Patients with suspected PAOD were examined with four-station MRA at a 3.0 T MR system. The MRA protocol consisted of a hybrid technique with two contrast media injections, the first one for visualization of the calf and foot vasculature (non-moving-table technique), the second one for imaging the aortoiliacal and femoral arteries (moving-table technique). For the femoropopliteal and calf station a randomly segmented central k-space ordering (contrast-enhanced timing-robust angiography [CENTRA]) was used. MR-images were analyzed independently by two radiologists with regard to image quality, venous overlap and grade of stenosis. In 6 patients digital subtraction angiography was performed within the following 7 days and evaluated by two radiologists in consensus with regard to the grade of stenosis. The vasculature-tree of each leg was divided in 12 segments, and 3 anatomical regions (iliacal, femoropopliteal, calf/foot).
490 and 488 of 495 arterial segments were visualized with diagnostic image quality by observer 1 and observer 2, respectively. Image quality was excellent in 470 and 457 arterial segments, respectively. Only 4 segments were rendered as non-diagnostic due to venous overlap. Relevant arterial stenoses (50-99%) were detected in 43 and 47 segments by observer 1 and observer 2, 66 and 65 arterial segments, respectively, were interpreted as occluded.
The hybrid MRA protocol at 3.0 T offers high diagnostic quality for the whole peripheral arterial tree without venous contamination at high spatial resolution.
本研究的目的是描述在3.0 T系统下对下肢进行对比增强磁共振血管造影(MRA),以评估外周动脉闭塞性疾病(PAOD)患者的高分辨率图像。
21例疑似PAOD患者在3.0 T MR系统上进行四部位MRA检查。MRA方案包括一种混合技术,注射两种造影剂,第一种用于显示小腿和足部血管(非移动床技术),第二种用于对腹主动脉髂动脉和股动脉成像(移动床技术)。对于股腘动脉和小腿部位,采用随机分段中心k空间排序(对比增强定时稳健血管造影术[CENTRA])。两名放射科医生独立分析MR图像的图像质量、静脉重叠和狭窄程度。6例患者在接下来的7天内进行了数字减影血管造影,并由两名放射科医生就狭窄程度达成共识进行评估。每条腿的血管树分为12个节段和3个解剖区域(髂部、股腘部、小腿/足部)。
观察者1和观察者2分别以诊断图像质量显示了495个动脉节段中的490个和488个。图像质量在470个和457个动脉节段中分别为优秀。仅4个节段因静脉重叠而诊断为非诊断性。观察者1和观察者2分别在43个和47个节段中检测到相关动脉狭窄(50 - 99%),分别有66个和65个动脉节段被解释为闭塞。
3.0 T的混合MRA方案在高空间分辨率下为整个外周动脉树提供了高诊断质量,且无静脉污染。