Muzii Ludovico
Department of Obstetrics and Gynecology, Campus Bio-Medico University, Rome, Italy.
J Minim Invasive Gynecol. 2006 Nov-Dec;13(6):535-8. doi: 10.1016/j.jmig.2006.06.010.
Medicated intrauterine systems (IUSs) are intrauterine devices that act by means of the local release of a medication. The levonorgestrel (LNG)-IUS is a T-shaped device that releases the progestogen LNG directly into the uterine cavity. The LNG-IUS can be used with noncontraceptive, therapeutic intent for idiopathic menorrhagia, hormonal replacement therapy in conjunction with oral or transdermal estrogens, and endometriosis or adenomyosis-associated pain. For this last indication, however, the use of the LNG-IUS is still under clinical investigation.
含药宫内节育系统（IUSs）是通过局部释放药物起作用的宫内节育器。左炔诺孕酮（LNG）-IUS是一种T形装置，可将孕激素LNG直接释放到子宫腔内。LNG-IUS可用于非避孕的治疗目的，如特发性月经过多、与口服或经皮雌激素联合的激素替代疗法，以及子宫内膜异位症或子宫腺肌病相关疼痛。然而，对于最后一种适应症，LNG-IUS的使用仍在临床研究中。
