Chuiko Grigorii M, Tillitt Donald E, Zajicek James L, Flerov Boris A, Stepanova Vera M, Zhelnin Yuri Y, Podgornaya Vera A
Institute of the Biology of Inland Waters (IBIW), Russian Academy of Sciences, Main St. No. 1, 152742 Borok, Nekouz, Yaroslavl, Russia.
Chemosphere. 2007 Mar;67(3):527-36. doi: 10.1016/j.chemosphere.2006.09.046. Epub 2006 Nov 13.
The Rybinsk Reservoir (Russia) is the largest artificial waterbody in Europe (4550 km2) and provides drinking water for population of the cities located along the coast line. Industrialization in Cherepovets at the northeastern portion of the reservoir, including one of the largest metallurgical facilities in Europe, has resulted in chemical contamination of the reservoir. The extent of polychlorinated biphenyls (PCB) contamination in bream liver, a common fish species, taken from six locations in the Rybinsk Reservoir and Volga River, and biochemical and morphometric biomarkers of fish health were investigated. Liver PCB concentrations ranged from non-detected to 3.4 microg/g wet wt of liver, with the greatest concentrations found in fish taken near the industrialized area in Sheksna Reach of Rybinsk Reservoir. The source of the bream contamination is the PCB pollution of bottom organisms and sediments conditioned with industrialization facilities of Cherepovets. The patterns of the PCB congeners in the livers of bream taken near Cherepovets were similar at all of the stations that were sampled around the reservoir and Volga River. Among the common fish health biomarkers used only liver total ChE activity and liver-somatic index in bream near Cherepovets can reflect environmental pollution. Other morphometric (FCF, Clark's condition factors, and spleen-somatic index) and biochemical (protein content and acetylcholinesterase activity in the brain) biomarkers related with fish health varied among locations, but were not correlated to the concentrations of PCBs in the bream livers.
雷宾斯克水库（俄罗斯）是欧洲最大的人工水体（面积4550平方公里），为沿岸城市居民提供饮用水。水库东北部切列波韦茨的工业化，包括欧洲最大的冶金设施之一，已导致该水库受到化学污染。研究了从雷宾斯克水库和伏尔加河六个地点采集的鲷鱼肝脏中多氯联苯（PCB）的污染程度，以及鱼类健康的生化和形态计量生物标志物。肝脏中PCB浓度范围从未检测到至3.4微克/克肝脏湿重，在雷宾斯克水库舍克斯纳河段工业化区域附近捕获的鱼类中浓度最高。鲷鱼污染的来源是切列波韦茨工业化设施造成的底部生物和沉积物的PCB污染。在水库和伏尔加河周围采样的所有站点，切列波韦茨附近捕获的鲷鱼肝脏中PCB同系物的模式相似。在常用的鱼类健康生物标志物中，只有切列波韦茨附近鲷鱼的肝脏总胆碱酯酶活性和肝脏体指数能反映环境污染。其他与鱼类健康相关的形态计量（FCF、克拉克条件因子和脾脏体指数）和生化（脑中蛋白质含量和乙酰胆碱酯酶活性）生物标志物在不同地点有所不同，但与鲷鱼肝脏中PCB浓度无关。
