Luque P, García-Gil F A, Larraga J, Jiménez B, Tomé-Zelaya E, Serrano M T, Barrao M E
Hospital Clínico Universitario Lozano Blesa, Zaragoza, Spain.
Transplant Proc. 2006 Oct;38(8):2514-5. doi: 10.1016/j.transproceed.2006.08.031.
Alternaria alternata is a dematiaceous mold capable of causing systemic and dermatological infections in immunosuppressed patients. We present a case of a liver transplant patient with cutaneous alternariosis and no response to amphotericin B lipid or surgical debridement of the lesions. Treatment with intravenous voriconazole was initiated, followed by the oral protocol, with complete resolution of the lesions. Voriconazole is an efficient alternative for the treatment of cutaneous lesions produced by A alternata.
链格孢是一种暗色霉菌，能够在免疫抑制患者中引起全身感染和皮肤感染。我们报告一例肝移植患者发生皮肤链格孢病，对两性霉素B脂质体治疗或手术清创均无反应。开始采用静脉注射伏立康唑治疗，随后采用口服方案，皮损完全消退。伏立康唑是治疗链格孢引起的皮肤损害的有效替代药物。
