多器官捐献会影响心脏移植的存活率吗？

Does multiorgan donation influence survival in heart transplantation?

作者信息

Almenar-Pertejo M, Almenar L, Martínez-Dolz L, Campos J, Galán J, Gironés P, Salvador A

机构信息

Transplant Coordination, La Fe University Hospital, Valencia, Spain.

出版信息

Transplant Proc. 2006 Oct;38(8):2527-8. doi: 10.1016/j.transproceed.2006.08.020.

DOI:10.1016/j.transproceed.2006.08.020

PMID:17097989

Abstract

UNLABELLED

Current heart transplant survival in Spain at 1, 5, and 10 years is 80%, 70%, and 60%, respectively. Our objective was to establish how donor type affects survival in heart transplantation.

MATERIALS AND METHODS

This was a retrospective study of heart transplant recipients from 102 donors, divided into three types: (a) heart-liver-kidney donors (group I); (b) heart-liver-kidney-lung donors (group II); and (c) heart-liver-kidney-lung-pancreas donors (group III). We excluded retransplantations, pediatric transplantations, and cardiopulmonary transplantations. The outcome variable was the actuarial survival by type of donation. Statistical analysis was performed for event-free survival based on the Kaplan-Meier method (log-rank test).

RESULTS

Groups I, II, and III included 63, 26, and 13 donors, respectively. The survival curves showed similar values for all three groups (P > .05).

CONCLUSIONS

The different combinations of multiorgan donation do not entail a poorer prognosis in terms of cardiac transplant patient survival.

摘要

未标注

目前西班牙心脏移植术后1年、5年和10年的生存率分别为80%、70%和60%。我们的目的是确定供体类型如何影响心脏移植的生存率。

材料与方法

这是一项对102名供体的心脏移植受者进行的回顾性研究，供体分为三种类型：(a)心-肝-肾供体（I组）；(b)心-肝-肾-肺供体（II组）；(c)心-肝-肾-肺-胰腺供体（III组）。我们排除了再次移植、儿科移植和心肺移植。观察变量是按捐赠类型计算的精算生存率。基于Kaplan-Meier方法（对数秩检验）对无事件生存率进行统计分析。