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活体肾供体发展为终末期肾病。

Living kidney donors developing end-stage renal disease.

作者信息

Fehrman-Ekholm I, Nordén G, Lennerling A, Rizell M, Herlitz H, Nielsen F-D, Storkamp O, Deurell S-I, Olausson M

机构信息

Department of Transplantation and Liver Surgery, Sahlgrenska University Hospital, Göteborg, Sweden.

出版信息

Transplant Proc. 2006 Oct;38(8):2642-3. doi: 10.1016/j.transproceed.2006.07.024.

Abstract

The incidence of end-stage kidney failure (ESRF) was analyzed among the cohort of 1112 living kidney donors who underwent nephrectomy from 1965 through 2005. It was found that at least six persons had developed ESRF at 14 to 27 years (median = 20 years), following donation. Five of six were men. Five were parents and one, a sibling. The diagnoses were nephrosclerosis (n = 4), postrenal failure (n = 1), and renal carcinoma (n = 1). One donor, aged 45 years, underwent kidney transplantation.

摘要

对1965年至2005年间接受肾切除术的1112名活体肾供者队列中的终末期肾衰竭(ESRF)发病率进行了分析。结果发现,至少有6人在捐献后14至27年(中位数=20年)出现了ESRF。6人中有5名男性。5人为父母,1人为兄弟姐妹。诊断结果为肾硬化(n=4)、肾后性肾衰竭(n=1)和肾癌(n=1)。一名45岁的供者接受了肾移植。

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