Dhamala Mukeshwar, Assisi Collins G, Jirsa Viktor K, Steinberg Fred L, Kelso J A Scott
Department of Biomedical Engineering, University of Florida, Gainesville, FL 33611, USA.
Neuroimage. 2007 Jan 15;34(2):764-73. doi: 10.1016/j.neuroimage.2006.07.044. Epub 2006 Nov 13.
How does the brain integrate information from different senses into a unitary percept? What factors influence such multisensory integration? Using a rhythmic behavioral paradigm and functional magnetic resonance imaging, we identified networks of brain regions for perceptions of physically synchronous and asynchronous auditory-visual events. Measures of behavioral performance revealed the existence of three distinct perceptual states. Perception of asynchrony activated a network of the primary sensory, prefrontal, and inferior parietal cortices, perception of synchrony disengaged the inferior parietal cortex and further recruited the superior colliculus, and when no clear percept was established, only the residual areas comprised of prefrontal and sensory areas were active. These results indicate that distinct percepts arise within specific brain sub-networks, the components of which are differentially engaged and disengaged depending on the timing of environmental signals.
大脑如何将来自不同感官的信息整合为一个统一的感知？哪些因素会影响这种多感官整合？通过一种节律性行为范式和功能磁共振成像，我们确定了用于感知物理同步和异步视听事件的脑区网络。行为表现的测量结果揭示了三种不同感知状态的存在。异步感知激活了初级感觉、前额叶和顶下皮质的网络，同步感知使顶下皮质脱离，并进一步激活了上丘，而当没有明确的感知形成时，只有由前额叶和感觉区域组成的残余区域处于活跃状态。这些结果表明，不同的感知在特定的脑子网中产生，其组成部分根据环境信号的时间差异地参与和脱离。
