Haan J, van Kleef J W, Bloem B R, Zwartendijk J, Lanser J B, Brand R, van der Does I G, Krul E J, Elshove H M, Moll A C
Department of Neurology, University Hospital Leiden, The Netherlands.
J Am Geriatr Soc. 1991 Jun;39(6):596-600. doi: 10.1111/j.1532-5415.1991.tb03600.x.
Cognitive functions in 53 elderly men who underwent a transurethral prostatectomy were assessed pre-operatively and 4 days and 3 months post-operatively. Thirteen patients had a preference for one particular type of anesthesia, and the remaining 40 were randomly allocated to receive either spinal or general anesthesia. Cognitive function was not different between the groups receiving different types of anesthesia at either time point and did not decrease post-operatively. No pre- or perioperative variable could distinguish the subgroup of patients who had a post-operative decrease of 2 points or more on the Mini-Mental State Examination. No difference in post-operative performance was found in the patient groups with pre-operative Mini-Mental State Examination scores above or under their age-specific norm. It is concluded that neither hospitalization nor the two forms of anesthesia investigated cause a decrease in cognitive function in elderly men.
对53名接受经尿道前列腺切除术的老年男性的认知功能在术前、术后4天和术后3个月进行了评估。13名患者偏爱一种特定类型的麻醉，其余40名患者被随机分配接受脊髓麻醉或全身麻醉。在两个时间点，接受不同类型麻醉的组之间认知功能没有差异，且术后认知功能没有下降。没有术前或围手术期变量能够区分出在简易精神状态检查中术后下降2分或更多的患者亚组。术前简易精神状态检查得分高于或低于其年龄特异性正常值的患者组在术后表现上没有差异。得出的结论是，住院治疗以及所研究的两种麻醉形式均不会导致老年男性认知功能下降。
