Suppr超能文献

自发性气胸行胸腔闭式引流时无需使用抗生素:一项观察性病例研究。

Antibiotics are not needed during tube thoracostomy for spontaneous pneumothorax: an observational case study.

作者信息

Olgac Guven, Aydogmus Umit, Mulazimoglu Lutfiye, Kutlu Cemal Asim

机构信息

Department of Thoracic Surgery, Sureyyapasa Chest and Cardiovascular Diseases Teaching and Research Hospital, Istanbul, Turkey.

出版信息

J Cardiothorac Surg. 2006 Nov 13;1:43. doi: 10.1186/1749-8090-1-43.

Abstract

BACKGROUND

Usefulness of prophylactic antibiotics following tube thoracostomy remains controversial in the literature. In this study, we aimed to investigate the consequences of closed tube thoracostomy for primary spontaneous pneumothorax without the use of antibiotics.

METHODS

One-hundred and nineteen patients underwent tube thoracostomy for primary spontaneous pneumothorax. None of them received prophylactic antibiotic treatment. Eight patients with prolonged air leak undergoing either video assisted thoracoscopic surgery or thoracotomy were excluded.

RESULTS

Of the remaining 111 (104 male and 7 female), 28 (25%) patients developed some induration around the entry site of chest tube that settled without further treatment. White blood cell count was high without any other evidence of infection in 12 (11%) patients and returned to its normal levels before discharge home in all. There was also some degree of fever not lasting for more than 48 hours in 8 (7%) patients. Bacterial cultures from suspected sites did not reveal any significant growth in these patients.

CONCLUSION

Prophylactic antibiotic treatment seems avoidable during closed tube thoracostomy for primary spontaneous pneumothorax. This policy was not only cost-effective but also prevented our patients from detrimental properties of unnecessary antibiotic use, such as development of drug resistance and undesirable side effects.

摘要

背景

文献中对于胸腔闭式引流术后预防性使用抗生素的有效性仍存在争议。在本研究中,我们旨在探讨不使用抗生素进行原发性自发性气胸胸腔闭式引流的后果。

方法

119例患者因原发性自发性气胸接受胸腔闭式引流。他们均未接受预防性抗生素治疗。8例持续漏气并接受电视辅助胸腔镜手术或开胸手术的患者被排除。

结果

在其余111例患者(104例男性和7例女性)中,28例(25%)患者在胸管置入部位周围出现一些硬结,未经进一步治疗即自行消退。12例(11%)患者白细胞计数升高,但无任何其他感染证据,且在出院前均恢复至正常水平。8例(7%)患者还出现了程度不一的发热,但持续时间不超过48小时。这些患者可疑部位的细菌培养均未发现任何显著生长。

结论

原发性自发性气胸胸腔闭式引流期间似乎可避免预防性抗生素治疗。这一策略不仅具有成本效益,还能使我们的患者避免不必要使用抗生素的有害影响,如耐药性的产生和不良副作用。

相似文献

3
[Spontaneous pneumothorax: retrospective analysis of 348 cases].
Ulus Travma Acil Cerrahi Derg. 2009 Jul;15(4):367-70.
9
Surgical management of spontaneous pneumothorax.自发性气胸的外科治疗
Thorac Cardiovasc Surg. 1984 Jun;32(3):165-9. doi: 10.1055/s-2007-1023375.

本文引用的文献

1
Antibiotic prophylaxis in elective thoracic surgery: cefuroxime versus cefepime.
Thorac Cardiovasc Surg. 2003 Apr;51(2):84-8. doi: 10.1055/s-2003-38991.
2
BTS guidelines for the management of spontaneous pneumothorax.英国胸科学会自发性气胸管理指南。
Thorax. 2003 May;58 Suppl 2(Suppl 2):ii39-52. doi: 10.1136/thorax.58.suppl_2.ii39.
5
Pneumothorax: experience with 1,199 patients.气胸:1199例患者的经验
Chest. 2000 May;117(5):1279-85. doi: 10.1378/chest.117.5.1279.

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验