Macura Katarzyna J, Ouwerkerk Ronald, Jacobs Michael A, Bluemke David A
Russell H. Morgan Department of Radiology and Radiological Sciences, Johns Hopkins Medical Institutions, 600 N Wolfe St, BLA-B 179 RAD, Baltimore, MD 21287, USA.
Radiographics. 2006 Nov-Dec;26(6):1719-34; quiz 1719. doi: 10.1148/rg.266065025.
The role of dynamic contrast material-enhanced magnetic resonance (MR) imaging of the breast as an adjunct to the conventional techniques of mammography and ultrasonography has been established in numerous research studies. MR imaging improves the detection and characterization of primary and recurrent breast cancers and allows evaluation of the response to therapy. The breast imaging lexicon published by the American College of Radiology allows a standardized and consistent description of the morphologic and kinetic characteristics of breast lesions; however, there are many challenges in the interpretation of breast enhancement patterns and kinetics, and many imaging and interpretation pitfalls must be considered. New breast MR imaging techniques that are based on the use of molecular markers of malignancy may help improve lesion characterization. The margin characteristics of a lesion and the intensity of its enhancement at MR imaging 2 minutes or less after contrast material injection are currently considered the most important features for breast lesion diagnosis.
乳腺动态对比剂增强磁共振(MR)成像作为乳腺X线摄影和超声等传统技术的辅助手段,其作用已在众多研究中得到确立。MR成像可提高原发性和复发性乳腺癌的检测及特征描述能力,并有助于评估治疗反应。美国放射学会发布的乳腺成像词典对乳腺病变的形态学和动力学特征进行了标准化且一致的描述;然而,乳腺强化模式和动力学的解读存在诸多挑战,必须考虑许多成像和解读陷阱。基于恶性肿瘤分子标志物使用的新型乳腺MR成像技术可能有助于改善病变特征描述。目前,病变的边缘特征及其在注射对比剂后2分钟或更短时间内MR成像的强化强度被认为是乳腺病变诊断的最重要特征。