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简短报告:收缩期心力衰竭退伍军人中β受体阻滞剂的使用情况

Brief report: beta-blocker use among veterans with systolic heart failure.

作者信息

Sinha Sanjai, Goldstein Matthew, Penrod Joan, Hochman Tsivia, Kamran Mohammad, Tenner Craig, Cohen Gabriela, Schwartz Mark D

机构信息

Department of Medicine, Bronx VA Medical Center, Bronx, NY, USA.

出版信息

J Gen Intern Med. 2006 Dec;21(12):1306-9. doi: 10.1111/j.1525-1497.2006.00601.x.

Abstract

BACKGROUND

Beta-blockers reduce mortality in patients with systolic chronic heart failure (CHF), yet prescription rates have remained low among primary care providers.

OBJECTIVE

To determine the beta-blocker prescription rate among patients with systolic CHF at primary care Veterans Affairs (VA) clinics, its change over time; and to determine factors associated with nonprescription.

DESIGN

Retrospective chart review.

SUBJECTS

Seven hundred and forty-five patients with diagnostic codes for CHF followed in primary care clinics at 3 urban VA Medical Centers.

MEASUREMENTS

Rate of beta-blocker prescription and comparison of patient characteristics between those prescribed versus those not prescribed beta-blockers.

RESULTS

Only 368 (49%) had documented systolic CHF. Eighty-two percent (303/368) of these patients were prescribed a beta-blocker. The prescription rate rose steadily over 3 consecutive 2-year time periods. Patients with more severely depressed ejection fractions were more likely to be on a beta-blocker than patients with less severe disease. Independent predictors of nonprescription included chronic obstructive pulmonary disease, asthma, depression, and age. Patients under 65 years old were 12 times more likely to receive beta-blockers than those over 85.

CONCLUSION

Primary care providers at VA Medical Centers achieved high rates of beta-blocker prescription for CHF patients. Subgroups with relative contraindications had lower prescription rates and should be targeted for quality improvement initiatives.

摘要

背景

β受体阻滞剂可降低收缩期慢性心力衰竭(CHF)患者的死亡率,但在初级保健提供者中,其处方率一直较低。

目的

确定初级保健退伍军人事务(VA)诊所中收缩期CHF患者的β受体阻滞剂处方率、随时间的变化情况;并确定与未开具处方相关的因素。

设计

回顾性病历审查。

研究对象

3家城市VA医疗中心的初级保健诊所中随访的745例有CHF诊断代码的患者。

测量指标

β受体阻滞剂处方率以及开具与未开具β受体阻滞剂患者的特征比较。

结果

仅368例(49%)有记录的收缩期CHF患者。其中82%(303/368)的患者开具了β受体阻滞剂。在连续3个2年时间段内,处方率稳步上升。射血分数严重降低的患者比病情较轻的患者更有可能使用β受体阻滞剂。未开具处方的独立预测因素包括慢性阻塞性肺疾病、哮喘、抑郁症和年龄。65岁以下的患者接受β受体阻滞剂的可能性是85岁以上患者的12倍。

结论

VA医疗中心的初级保健提供者为CHF患者开具β受体阻滞剂的比例较高。有相对禁忌证的亚组处方率较低,应作为质量改进举措的目标对象。

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