肺燕麦细胞癌的联合化疗
Combination chemotherapy in oat cell carcinoma of the lung.
作者信息
Nixon D W, Carey R W, Suit H D, Aisenberg A C
出版信息
Cancer. 1975 Sep;36(3):867-72. doi: 10.1002/1097-0142(197509)36:3<867::aid-cncr2820360307>3.0.co;2-1.
Abstract
Twenty-eight patients with oat cell carcinoma of the lung were treated with cyclophosphamide, vincristine, procarbazine, and prednisone with and without irradiation. Median survival was significantly increased in this treatment group (10 months) as compared to a retrospective radiation alone series (5 months). Intensive chemotherapy with this four-drug regimen represents an initial step in effective management of this disorder.
摘要
28例肺燕麦细胞癌患者接受了环磷酰胺、长春新碱、丙卡巴肼和泼尼松联合或不联合放疗的治疗。与单纯回顾性放疗系列（5个月）相比，该治疗组的中位生存期显著延长（10个月）。采用这种四联化疗方案的强化化疗是有效治疗这种疾病的第一步。
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