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给予利血平或6-羟基多巴胺后,鲻鱼吻端远侧部的超微结构、儿茶酚胺和催乳素含量

The ultrastructure, catecholamine, and prolactin contents of the rostral pars distalis of the fish Mugil platanus after reserpine or 6-hydroxydopamine administration.

作者信息

Zambrano D

出版信息

Cell Tissue Res. 1975 Oct 27;162(4):551-63. doi: 10.1007/BF00209354.

DOI:10.1007/BF00209354
PMID:171075
Abstract

The rostral pars distalis (RPD) of the teleost Mugil plantanus from animals pretreated with reserpine or 6-hydroxydopamine (6-HODA) were assayed for dopamine (DA) or noradrenaline (NA) or for prolactin hormone. Such determinations were coupled with electron microscopy. It was found that reserpine and 6-HODA produced a significant decrease in the content of DA, NA, and prolactin. Electron microscope studies revealed that prolactin cells became activated as judged by ultrastructural criteria. After 6-HODA treatment type "B" neurosecretory fibers entering the RPD became selectively destroyed. These observations lead us to suggest that prolactin secretion is under inhibitory control by type "B" neurosecretory fibers of adrenergic nature.

摘要

对用利血平或6-羟基多巴胺(6-HODA)预处理过的硬骨鱼普拉塔凡鲻的吻端远侧部(RPD)进行多巴胺(DA)、去甲肾上腺素(NA)或催乳素的测定。这些测定与电子显微镜检查相结合。结果发现,利血平和6-HODA使DA、NA和催乳素的含量显著降低。电子显微镜研究表明,根据超微结构标准判断,催乳素细胞被激活。6-HODA处理后,进入RPD的“B”型神经分泌纤维被选择性破坏。这些观察结果使我们认为,催乳素的分泌受肾上腺素能性质的“B”型神经分泌纤维的抑制控制。

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本文引用的文献

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[STRUCTURAL AND ULTRASTRUCTURAL BASES OF DIENCEPHALO-HYPOPHYSEAL CORRELATIONS IN SELACHIANS AND TELEOSTS].[鲨鱼和硬骨鱼间脑-垂体相关性的结构和超微结构基础]
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Z Zellforsch Mikrosk Anat. 1970;110(4):496-516. doi: 10.1007/BF00330101.
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The median eminence of the bowfin, Amia calva L.雀鳝(Amia calva L.)的正中隆起
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Effects of 6-hydroxydopamine on catecholamine containing neurones in the rat brain.6-羟基多巴胺对大鼠脑中含儿茶酚胺神经元的影响。
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Z Zellforsch Mikrosk Anat. 1971;121(2):232-43.