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非洲爪蟾(非洲爪蟾,非洲爪蟾)侧线感觉细胞传入突触的超微结构和药理学研究。

Ultrastructural and pharmacological studies on the afferent synapse of lateral-line sensory cells of the African clawed toad, Xenopus laevis.

作者信息

Monaghan P

出版信息

Cell Tissue Res. 1975 Nov 7;163(2):239-47. doi: 10.1007/BF00221730.

DOI:10.1007/BF00221730
PMID:171077
Abstract

Lateral-line sensory cells of Xenopus show considerable similarity to central nervous system synapses in their responses to the zinc iodide-osmium tetroxide, and bismuth-iodide cytochemical staining techniques. Both reserpine and FLA-63 cause a reduction in the diameter and electron density of the synaptic bars, and a dramatic loss of synaptic vesicles surrounding the bars. Aminooxy acetic acid and 3-mercaptopropionic acid cause no significant changes in the sensory-cell afferent synaptic apparatus. The results are discussed in the light of the known effects of the drugs. It is concluded that a monoamine rather than an amino acid may act as the afferent transmitter.

摘要

非洲爪蟾的侧线感觉细胞在对碘化锌 - 四氧化锇和碘化铋细胞化学染色技术的反应中,与中枢神经系统突触表现出相当大的相似性。利血平和FLA - 63都会导致突触条直径和电子密度减小,以及突触条周围突触小泡的显著丢失。氨氧基乙酸和3 - 巯基丙酸对感觉细胞传入突触装置没有显著影响。根据药物的已知作用对结果进行了讨论。得出的结论是,可能是单胺而非氨基酸充当传入神经递质。

相似文献

1
Ultrastructural and pharmacological studies on the afferent synapse of lateral-line sensory cells of the African clawed toad, Xenopus laevis.非洲爪蟾(非洲爪蟾,非洲爪蟾)侧线感觉细胞传入突触的超微结构和药理学研究。
Cell Tissue Res. 1975 Nov 7;163(2):239-47. doi: 10.1007/BF00221730.
2
Comparative study of ultrastructures of the lateral-line organs and the palatal taste organs in the African clawed toad, Xenopus laevis.
Anat Rec. 1982 Dec;204(4):371-81. doi: 10.1002/ar.1092040411.
3
Ultrastructure of the lateral-line sense organs of the ratfish, Chimaera monstrosa.银鲛(Chimaera monstrosa)侧线感觉器官的超微结构
Cell Tissue Res. 1981;215(3):651-65. doi: 10.1007/BF00233539.
4
Fine structure of the afferent synapse of the hair cells in the saccular macula of the goldfish, with special reference to the anastomosing tubules.金鱼球囊斑毛细胞传入突触的精细结构,特别提及吻合小管。
J Neurocytol. 1977 Aug;6(4):361-73. doi: 10.1007/BF01178223.
5
Synaptic morphology of the carotid body of the domestic fowl.家鸡颈动脉体的突触形态
Cell Tissue Res. 1975 Oct 27;162(4):459-73. doi: 10.1007/BF00209346.
6
Effects of light and dark upon photoreceptor synapses in the retina of Xenopus laevis.
Cell Tissue Res. 1976 Oct 6;173(2):211-20. doi: 10.1007/BF00221376.
7
Large inclusions in receptor cells of the amphibian lateral line.两栖动物侧线受体细胞中的大包涵体。
Am J Anat. 1973 Dec;138(4):465-79. doi: 10.1002/aja.1001380405.
8
The pharmacology of efferent synapses in the lateral-line system of Xenopus laevis.非洲爪蟾侧线系统传出突触的药理学
J Exp Biol. 1971 Jun;54(3):643-58. doi: 10.1242/jeb.54.3.643.
9
Synaptic morphology and differences in sensitivity.
Science. 1985 Apr 12;228(4696):197-9. doi: 10.1126/science.3975637.
10
Demonstration of dopamine in electron-dense synaptic vesicles in the pars intermedia of Xenopus laevis, by freeze substitution and postembedding immunogold electron microscopy.
Histochemistry. 1991;96(6):505-10. doi: 10.1007/BF00267076.

引用本文的文献

1
Destruction of afferent nerve terminals in the inner ear of frog by aminooxyactic acid.用氨氧基乙酸破坏青蛙内耳的传入神经末梢。
Experientia. 1976 Dec 15;32(12):1545-7. doi: 10.1007/BF01924443.
2
Evidence that 5-HT is not the afferent transmitter in the cochlea.5-羟色胺并非耳蜗传入神经递质的证据。
Exp Brain Res. 1977 Oct 24;30(1):141-3. doi: 10.1007/BF00237864.
3
Evidence that catecholamines are not the afferent transmitter in the cochlea.儿茶酚胺并非耳蜗传入神经递质的证据。

本文引用的文献

1
EVIDENCE FOR A FALSE NEUROCHEMICAL TRANSMITTER AS A MECHANISM FOR THE HYPOTENSIVE EFFECT OF MONOAMINE OXIDASE INHIBITORS.作为单胺氧化酶抑制剂降压作用机制的假性神经化学递质的证据。
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The inhibition of gamma aminobutyric-alpha-ketoglutaric acid transaminase in vitro and in vivo by amino-oxyacetic acid.氨氧基乙酸在体外和体内对γ-氨基丁酸-α-酮戊二酸转氨酶的抑制作用。
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Structure of the nerve endings on the external hair cells of the guinea pig cochlea as studied by serial sections.通过连续切片研究豚鼠耳蜗外毛细胞上神经末梢的结构。
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Elevation of gamma-aminobutyric acid in brain: selective inhibition of gamma-aminobutyric-alpha-ketoglutaric acid transaminase.脑中γ-氨基丁酸水平的升高:γ-氨基丁酸-α-酮戊二酸转氨酶的选择性抑制
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Neurophysiological studies on hearing in goldfish.金鱼听觉的神经生理学研究。
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7
Enzymatic digestion of synaptic ribbons in amphibian retinal photoreceptors.两栖类视网膜光感受器中突触带的酶解作用。
Brain Res. 1971 Feb 5;25(3):571-7. doi: 10.1016/0006-8993(71)90461-6.
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Mercaptopropionic acid: a convulsant that inhibits glutamate decarboxylase.巯基丙酸:一种抑制谷氨酸脱羧酶的惊厥剂。
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Studies on central and peripheral noradrenaline neurons using a new dopamine-(beta)-hydroxylase inhibitor.使用新型多巴胺-β-羟化酶抑制剂对中枢和外周去甲肾上腺素能神经元的研究。
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10
Histochemical localization of acetylcholinesterase (AChE) activity in the inner ear.内耳中乙酰胆碱酯酶(AChE)活性的组织化学定位。
Acta Otolaryngol Suppl. 1971;279:1-50.