Fleetwood J A, Smith P A
Clin Chim Acta. 1975 Oct 1;64(1):51-5. doi: 10.1016/0009-8981(75)90143-6.
Using a relatively simple 11-deoxy-17-oxosteroid assay a group of hirsute patients have been studied before and following the administration of ACTH. These patients were selected on the basis that each showed an exaggerated response of urinary testosterone excretion to ACTH stimulation. Fifteen of eighteen patients were found to show an exaggerated urinary 11-deoxy-17-oxosteroid response to ACTH stimulation in addition to the excessive urinary testosterone response, suggesting that dysfunction of the adrenal cortex might be a factor contributing to the hirsutism of these fifteen patients.
通过一种相对简单的11 - 脱氧 - 17 - 氧代类固醇测定法，对一组多毛症患者在注射促肾上腺皮质激素（ACTH）前后进行了研究。这些患者的入选依据是，每个人的尿睾酮排泄对ACTH刺激均表现出过度反应。在18名患者中，有15名除了尿睾酮反应过度外，其尿11 - 脱氧 - 17 - 氧代类固醇对ACTH刺激也表现出过度反应，这表明肾上腺皮质功能障碍可能是导致这15名患者多毛症的一个因素。
