Blum M, Kunert K, Nolte S, Riehemann S, Palme M, Peschel T, Dick M, Dick H B
Klinik für Augenheilkunde, Helios-Klinikum Erfurt, Nordhäusser-Strasse 74, 99089 Erfurt.
Ophthalmologe. 2006 Dec;103(12):1014-9. doi: 10.1007/s00347-006-1449-x.
Presbyopia is by far the most common refractive error worldwide, with no permanent therapeutic option available. All efforts to restore accommodation by the use of surgery have not led to a generally accepted therapy. However, there is evidence from an animal model that the use of a femtosecond (fs) laser might influence the modulus of elasticity in the lens. Fs-laser impulses can create intralenticular disruption in animal eyes as well as human cadaver lenses and improve elasticity. The concept of treating presbyopia with fs-laser requires a new, complex theory combining the optical and the mechanical aspects of accommodation in the eye. Diagnostic tools for measuring optical change in power and geometrical modification as the eye views from far to near are needed to obtain objective clinical data. A non-invasive treatment of presbyopia to restore accommodation might be possible in the future.
老花眼是目前全球最常见的屈光不正问题，尚无永久性治疗方法。所有通过手术恢复调节功能的努力都未产生被广泛接受的疗法。然而，动物模型的证据表明，使用飞秒（fs）激光可能会影响晶状体的弹性模量。飞秒激光脉冲可在动物眼睛以及人类尸体晶状体中造成晶状体内部破坏并改善弹性。用飞秒激光治疗老花眼的概念需要一种结合眼睛调节光学和机械方面的全新复杂理论。需要用于测量眼睛从远到近观察时屈光力的光学变化和几何形态改变的诊断工具，以获取客观的临床数据。未来有可能实现对老花眼的无创治疗以恢复调节功能。
