Kammel Robert, Ackermann Roland, Mai Torsten, Damm Christoph, Nolte Stefan
Institute of Applied Physics, Abbe Center of Photonics, Friedrich-Schiller-Universität Jena, Max-Wien-Platz 1, Jena, Germany.
Optom Vis Sci. 2012 Jun;89(6):908-15. doi: 10.1097/OPX.0b013e318255da87.
To investigate porcine lenses in a lens stretcher with regard to presbyopia corrective procedures.
A lens stretching device was designed, which allows to simultaneously determine all relevant geometrical and optical parameters at each stretch position. The setup was used to compare the optical and geometrical lens properties of young slaughter pigs (n = 5) with older sows (n = 7).
The change of optical power with stretching is about five times larger for young porcine lenses than for sows. For young pigs, the gradient index profile of the crystalline lens significantly contributes to the induced accommodation amplitude.
We have shown that sow lenses are a suitable model for in vitro experiments on possible treatments for presbyopia. The rapid decrease in the induced accommodation amplitude with age may be explained by a reduced change of all geometrical lens parameters, which in turn leads to a smaller contribution of the gradient index profile to accommodation.
在晶状体拉伸器中研究猪晶状体用于老花眼矫正手术。
设计了一种晶状体拉伸装置，该装置能够在每个拉伸位置同时测定所有相关的几何和光学参数。利用该装置比较了幼年屠宰猪（n = 5）和成年母猪（n = 7）晶状体的光学和几何特性。
幼年猪晶状体的屈光力随拉伸的变化比母猪的大约大五倍。对于幼年猪，晶状体的梯度折射率分布对诱导的调节幅度有显著贡献。
我们已经表明，母猪晶状体是用于老花眼可能治疗方法体外实验的合适模型。随着年龄增长，诱导调节幅度的快速下降可能是由于晶状体所有几何参数的变化减少，这反过来导致梯度折射率分布对调节的贡献较小。
