[原子吸收光谱法测定抗肿瘤中药中的15种微量元素]

[Determination of 15 trace elements in antineoplastic traditional Chinese medicine by atomic absorption spectrometry].

作者信息

Liu Yan-Ming, Wang Hui, Han Jin-Tu, Lou Zhi-Ge, Yue Shi-Ping

机构信息

College of Chemistry and Chemical Engineering, Xinyang Normal University, Xinyang 464000, China.

出版信息

Guang Pu Xue Yu Guang Pu Fen Xi. 2006 Sep;26(9):1728-31.

PMID:17112056

Abstract

Five kinds of antineoplastic traditional Chinese medicines including fufangtianxian capsule, xiaoaiping tablet, zhiling capsule, shenlian capsule and shenlinglan capsule were digested with HNO3-HCl mixed acid. The fifteen trace elements including calcium, magnesium, potassium, sodium, iron, zinc, manganese, cobalt, nickel, chromium, silver, copper, strontium, cadmium and lead in the above-mentioned drugs were determined by atomic adsorption spectrometry. The effects of the kinds of mixed acid, the ratio of HNO3 to HCl in the mixed acid, the volume of digesting solution and the digesting time were also investigated in detail. The results obtained show that the concentrations of Ca, Mg, K, Na, Fe, Zn, Mn, Co and Ni in the five kinds of antineoplastic Chinese traditional medicines are higher than those of other elements.

摘要

采用硝酸 - 盐酸混合酸消解复方天仙胶囊、消癌平片、志苓胶囊、参莲胶囊和参灵蓝胶囊这5种抗肿瘤中药。采用原子吸收光谱法测定上述药物中钙、镁、钾、钠、铁、锌、锰、钴、镍、铬、银、铜、锶、镉和铅这15种微量元素。并详细考察了混合酸种类、混合酸中硝酸与盐酸的比例、消解液体积和消解时间的影响。结果表明，5种抗肿瘤中药中钙、镁、钾、钠、铁、锌、锰、钴和镍的含量高于其他元素。