• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

[Monoclonal antibodies against determinants on human MHC class II antigens].

作者信息

Eichler W, Seifert M, Fiebig H

机构信息

Bereich Tierphysiologie und Immunbiologie, Karl-Marx-Universität Leipzig.

出版信息

Allerg Immunol (Leipz). 1990;36(4):309-20.

PMID:1711285
Abstract

Monoclonal antibodies against different non-polymorphic determinants of HLA class II antigens are described. The epitopes are present on HLA-DR and HLA-DQ gene products as detected by monoclonal antibody BL-Ia/l, and at HLA-DR and HLA-DP gene products which are recognized by monoclonal antibody BL-Ia/4. Another epitope recognized by the monoclonal antibody BL-Ia/DQ is only found on DQ molecules. The monoclonal antibodies BL-Ia/1, BL-Ia/4, and BL-Ia/5 are directed against the beta-subunit of 29 kDa/35 kDa class II heterodimer molecules. The recognized epitopes are shown to be not dependent on the association of the alpha- and beta-chains.

摘要

相似文献

1
[Monoclonal antibodies against determinants on human MHC class II antigens].
Allerg Immunol (Leipz). 1990;36(4):309-20.
2
Monoclonal antibodies to HLA-DP, DQ, and DR determinants: functional effects on the activation and proliferation of normal and EBV-transformed B cells.针对HLA-DP、DQ和DR决定簇的单克隆抗体：对正常和EB病毒转化的B细胞激活和增殖的功能影响
Exp Hematol. 1986 Oct;14(9):887-95.
3
Monoclonal antibodies to human major histocompatibility complex class II antigens.
Crit Rev Immunol. 1987;8(1):23-48.
4
Human class II antigens. Implication of carbohydrate in the determinants recognized by several antihuman class II monoclonal antibodies.
Transplantation. 1986 Dec;42(6):647-52.
5
Complexity of the supertypic HLA-DRw53 specificity: two distinct epitopes differentially expressed on one or all of the DR beta-chains depending on the HLA-DR allotype.超型HLA - DRw53特异性的复杂性：根据HLA - DR同种异型，两个不同的表位在一条或所有DRβ链上差异表达。
J Immunol. 1986 Oct 15;137(8):2618-26.
6
Monoclonal antibodies to polymorphic epitopes on Ia antigens: three independent groups of determinants expressed on DRw6 homozygous cells.针对Ia抗原多态性表位的单克隆抗体：在DRw6纯合细胞上表达的三组独立决定簇。
Eur J Immunol. 1984 Aug;14(8):739-44. doi: 10.1002/eji.1830140813.
7
Analysis of the molecular specificities of anti-class II monoclonal antibodies by using L cell transfectants expressing HLA class II molecules.利用表达HLA II类分子的L细胞转染子分析抗II类单克隆抗体的分子特异性
J Immunol. 1988 Sep 15;141(6):2158-64.
8
Ia molecular localization of the DRw52 allodeterminant and the DRw52-like determinants defined by monoclonal antibodies.DRw52同种异体决定簇及由单克隆抗体所定义的DRw52样决定簇的Ia分子定位。
J Immunol. 1985 Oct;135(4):2642-6.
9
Two distinct class II molecules encoded by the genes within HLA-DR subregion of HLA-Dw2 and Dw12 can act as stimulating and restriction molecules.由HLA - Dw2和Dw12的HLA - DR亚区内基因编码的两种不同的II类分子可作为刺激分子和限制分子。
J Immunol. 1985 Aug;135(2):1288-98.
10
A novel HLA class II molecule (DR alpha-DQ beta) created by mismatched isotype pairing.一种由错配同种型配对产生的新型HLA II类分子（DRα-DQβ）。
Nature. 1987;329(6137):339-41. doi: 10.1038/329339a0.