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全膝关节置换术后回输失血对肺灌注的影响:一项前瞻性对照研究。

Effect of shed blood retransfusion on pulmonary perfusion after total knee arthroplasty: a prospective controlled study.

作者信息

Altinel Levent, Kaya Eser, Kose Kamil Cagri, Fidan Fatma, Ergan Volkan, Fidan Hüseyin

机构信息

Department of Orthopedics and Traumatology, School of Medicine, Afyon Kocatepe University, Afyon, Turkey.

出版信息

Int Orthop. 2007 Dec;31(6):837-44. doi: 10.1007/s00264-006-0265-x. Epub 2006 Nov 4.

Abstract

Postoperative shed blood retransfusion (autotransfusion) is a commonly used salvage method following major surgical operations, such as total knee arthroplasty (TKA). The systemic effects of shed blood are still unclear. We studied the effect of residual substances in the retransfused shed blood, on lung perfusion after TKA. Fifteen unilateral and one bilateral TKAs were performed with autotransfusion (the study group) and 15 unilateral and three bilateral TKAs were performed in a control group. Lung X-rays, arterial blood gases (ABG), D-dimer values, and lung perfusion scintigraphies were performed preoperatively and postoperatively. A mean of 300.0 +/- 335.6 ml of bank blood was needed in the autotransfusion group and a mean of 685.7 +/- 365.5 ml of bank blood was needed in the control group (p=0.001). There was a postoperative segmental perfusion defect at the lateral segment of the superior lobe of the left lung in one patient of the control group and he also had risk factors for thrombosis. Although both groups had a decrease in lung perfusion postoperatively, there were no significant differences among the groups regarding the lung perfusion scintigraphy, chest X-rays, ABG, and D-dimer values. In conclusion, although pulmonary perfusion diminishes following TKA, shed blood retransfusion does not add any risk to pulmonary perfusion.

摘要

术后失血回输(自体输血)是全膝关节置换术(TKA)等大型外科手术后常用的一种挽救方法。失血的全身影响仍不清楚。我们研究了TKA术后回输失血液中的残留物质对肺灌注的影响。对15例单侧和1例双侧TKA患者进行了自体输血(研究组),对15例单侧和3例双侧TKA患者进行了对照。术前和术后均进行了肺部X光检查、动脉血气(ABG)分析、D-二聚体值测定和肺灌注闪烁扫描。自体输血组平均需要300.0±335.6ml库存血,对照组平均需要685.7±365.5ml库存血(p=0.001)。对照组1例患者术后左肺上叶外侧段出现节段性灌注缺损,该患者也有血栓形成的危险因素。虽然两组术后肺灌注均下降,但在肺灌注闪烁扫描、胸部X光检查、ABG分析和D-二聚体值方面,两组之间无显著差异。总之,虽然TKA术后肺灌注会降低,但失血回输不会增加肺灌注的任何风险。

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